Subcellular Stress Markers in Epithelial Ovarian Cancer.

Edina Amalia Wappler-Guzzetta, Eva Margittai, Krisztina Veszelyi, Shanel Pickard, Caroline Merwin, Attila Molvarec, Ibolya Czegle

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Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Edina Amalia Wappler-GuzzettaDivision of Transfusion Medicine, Department of Laboratory Medicine, University of California, San Francisco, CA 94143, USA.ORCID 0000-0002-2195-5960

Eva MargittaiInstitute of Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.

Krisztina VeszelyiInstitute of Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.

Shanel PickardDepartment of Laboratory Medicine, University of California, San Francisco, CA 94143, USA.

Caroline MerwinDelgado Community College, New Orleans, LA 70119, USA.

Attila MolvarecDepartment of Obstetrics and Gynecology, Semmelweis University, 1085 Budapest, Hungary.

Ibolya CzegleDepartment of Internal Medicine and Hematology, Semmelweis University, 1085 Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial ovarian cancer is one of the most lethal gynecological malignancies worldwide. Its development strongly depends on several genetic and environmental factors, with metabolic components and cellular redox homeostasis alterations playing a significant a role in its development and disease progression. In this review, we summarize the contribution of mitochondrial and endoplasmic reticulum (ER) stress in the pathogenesis of epithelial ovarian cancer along with their role as potential biomarkers and therapeutic targets, including proteins of glucose metabolism, mitochondrial fission and fusion, mitophagy, membrane-associated ring-CH-type finger 5 (MARCH5), A-kinase anchoring proteins (AKAPs), proteins regulating mitochondrial Ca

Indexed as

Biomarkers, TumorCarcinoma, Ovarian EpithelialEndoplasmic Reticulum StressOvarian NeoplasmsAnimalsEndoplasmic Reticulum Chaperone BiPFemaleHumansMitochondriaUnfolded Protein ResponseBiomarkers, TumorEndoplasmic Reticulum Chaperone BiPHSPA5 protein, humanendoplasmic reticulum stressepithelial ovarian cancermitochondrial stress

Identifiers

PMID41516218

DOI10.3390/ijms27010342

PMCPMC12785920

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.