Evidence map›Paper›PMID 41516184›Full record

ArticleInternational journal of molecular sciences2025

Serum Oncostatin M in Ulcerative Colitis Patients and Its Relation to Disease Activity.

Alina-Ecaterina Jucan, Georgiana-Elena Sarbu, Vasile-Claudiu Mihai, Carmen Atodiresei, Simona Juncu, Ioana-Ruxandra Mihai, Mariana Pavel-Tanasa, Daniela Constantinescu, Mihaela Dranga, Otilia Nedelciuc and 9 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Alina-Ecaterina JucanDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.ORCID 0000-0003-1694-3970
Georgiana-Elena SarbuDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.ORCID 0009-0008-1372-707X
Vasile-Claudiu MihaiDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.ORCID 0009-0003-6226-2196
Carmen AtodireseiDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.
Simona JuncuDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.
Ioana-Ruxandra MihaiDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.
Mariana Pavel-TanasaDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.ORCID 0000-0002-2802-5993
Daniela ConstantinescuDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.ORCID 0000-0003-0732-3745
Mihaela DrangaDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.
Otilia NedelciucDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.
Diana-Gabriela IosepDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.
Mihai DanciuDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.ORCID 0000-0002-0194-7832
Smaranda DiaconescuDepartment of Pediatrics, University of Medicine Titu Maiorescu, 040441 Bucharest, Romania.
Georgiana-Emmanuela Gîlca-BlanariuDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.ORCID 0000-0002-5590-6462
Andrei Mihai AndronicDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.ORCID 0009-0000-8314-0997
Elena ToaderDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.ORCID 0000-0002-7783-1203
Vasile-Liviu DrugDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.ORCID 0000-0002-7596-2656
Cristina Cijevschi PrelipceanDepartment of Gastroenterology, Institute of Gastroenterology and Hepatology, Saint Spiridon County Hospital, 700111 Iasi, Romania.
Catalina MihaiDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease; non-invasive biomarkers that accurately reflect the endoscopic and histological activity of UC require validation. Therefore, our study focused on exploring the potential of serum oncostatin M (OSM) as a biomarker for evaluating UC severity. A total of UC 89 eligible participants (≥18 years) underwent extensive clinical and paraclinical evaluation. Clinical, endoscopic, and histological activity were assessed using the partial Mayo score (pMS), the Mayo endoscopic score (MES), and the Nancy Histological Index (NHI), respectively. Serum OSM levels were determined by ELISA test and measured in pg/mL; fecal calprotectin (FC) was measured in µ/g. In our study, serum OSM was significantly associated with all four outcome measures: higher OSM levels predicted higher pMS (β = 0.471,

Indexed as

Colitis, UlcerativeOncostatin MAdultBiomarkersFemaleHumansLeukocyte L1 Antigen ComplexMaleMiddle AgedROC CurveSeverity of Illness IndexBiomarkersLeukocyte L1 Antigen ComplexOncostatin Mbiomarkerdisease activityendoscopic healinghistological healingoncostatin Mulcerative colitis

Identifiers

PMID41516184
PMCPMC12785645

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.