Evidence map›Paper›PMID 41516151›Full record

ArticleInternational journal of molecular sciences2025

Expression of Serum and Exosomal microRNA-34a in Subjects with Increased Fat Mass.

Jacqueline Alejandra Noboa-Velástegui, Rodolfo Iván Valdez-Vega, Jorge Castro-Albarran, Perla Monserrat Madrigal-Ruiz, Ana Lilia Fletes-Rayas, Sandra Luz Ruiz-Quezada, Martha Eloisa Ramos-Márquez, José de Jesús López-Jiménez, Iñaki Álvarez, Rosa Elena Navarro-Hernández

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jacqueline Alejandra Noboa-VelásteguiDepartamento de Biología Celular, Fisiología e Inmunología, Institut de Biotecnologia i Biomedicina, Campus de Bellaterra, Bellatera, 08193 Barcelona, Spain.ORCID 0000-0003-1990-2437
Rodolfo Iván Valdez-VegaPrograma de Doctorado en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Calle Sierra Mojada No. 950, Colonia Independencia, Guadalajara C.P. 44340, Mexico.ORCID 0000-0002-0317-2145
Jorge Castro-AlbarranDepartamento de Ciencias de la Salud y Ecología Humana, División de Desarrollo Regional, Centro Universitario de la Costa Sur, Autlan de Navarro C.P. 48900, Mexico.ORCID 0000-0002-3355-067X
Perla Monserrat Madrigal-RuizUDG-CA-701, Inmunometabolismo en Enfermedades Complejas y Envejecimiento, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Calle Sierra Mojada No. 950, Colonia Independencia, Guadalajara C.P. 44340, Mexico.
Ana Lilia Fletes-RayasInstituto de Investigación en Enfermería y Salud Traslacional, Departamento de Enfermería Aplicada, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Calle Sierra Mojada No. 950, Colonia Independencia, Guadalajara C.P. 44340, Mexico.ORCID 0000-0003-3420-8574
Sandra Luz Ruiz-QuezadaDepartamento de Farmacobiología, Division de Ciencias Básicas, Centro Universitario de Ciencias Exactas e Ingenierias, Universidad de Guadalajara, Blvd. Gral. Marcelino García Barragán No. 1421, Colonia Olímpica, Guadalajara C.P. 44430, Mexico.ORCID 0000-0002-3895-5123
Martha Eloisa Ramos-MárquezInstituto de Investigación en Enfermedades Crónico Degenerativas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Calle Sierra Mojada No. 950, Colonia Independencia, Guadalajara C.P. 44340, Mexico.ORCID 0000-0003-4064-5578
José de Jesús López-JiménezLaboratorio de Ciencias Morfológico-Forenses y Medicina Molecular, Departamento de Morfología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Calle Sierra Mojada No. 950, Colonia Independencia, Guadalajara C.P. 44340, Mexico.ORCID 0000-0001-5499-0626
Iñaki ÁlvarezDepartamento de Biología Celular, Fisiología e Inmunología, Institut de Biotecnologia i Biomedicina, Campus de Bellaterra, Bellatera, 08193 Barcelona, Spain.ORCID 0000-0001-9484-0868
Rosa Elena Navarro-HernándezUDG-CA-701, Inmunometabolismo en Enfermedades Complejas y Envejecimiento, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Calle Sierra Mojada No. 950, Colonia Independencia, Guadalajara C.P. 44340, Mexico.ORCID 0000-0001-5531-5403

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs), particularly exosomes, are key mediators of intercellular communication, transporting biomolecules such as nucleic acids, lipids, and proteins that influence immune and metabolic pathways. In adipose tissue (AT), adipocyte-derived EVs (AdEVs) play a crucial role in maintaining metabolic homeostasis and have been implicated in obesity-related dysfunction. Among their bioactive cargo, microRNAs regulate post-transcriptional gene expression and participate in immunometabolic regulation. This study aimed to determine whether

Indexed as

Adipose TissueAdiposityExosomesMicroRNAsObesityAdultBiomarkersFemaleGene Expression RegulationHumansMaleMiddle AgedBiomarkersMicroRNAsMIRN34 microRNA, humanexosomesfat percentagemiR-34a

Identifiers

PMID41516151
PMCPMC12786089

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.