Evidence map›Paper›PMID 41516076›Full record

ArticleInternational journal of molecular sciences2025

AI/ML-Assisted Detection of

Bor-Jang Hwang, Oluwatunmise Akinniyi, Sharon Harrison, Denise Gibbs, Charles Waihenya, Andrew Gachii, Precious E Dike, Bethtrice Elliott, Fahmi Khalifa, Camille Ragin and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bor-Jang HwangDepartment of Biology, Morgan State University, Baltimore, MD 21251, USA.ORCID 0009-0001-4455-9266
Oluwatunmise AkinniyiDepartment of Electrical and Computer Engineering, Morgan State University, Baltimore, MD 21251, USA.ORCID 0009-0002-2744-5475
Sharon HarrisonCancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Denise GibbsCancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Charles WaihenyaThe African Caribbean Cancer Consortium, Philadelphia, PA 19111, USA.
Andrew GachiiThe African Caribbean Cancer Consortium, Philadelphia, PA 19111, USA.
Precious E DikeDepartment of Biology, Morgan State University, Baltimore, MD 21251, USA.ORCID 0000-0002-6279-3814
Bethtrice ElliottDepartment of Biology, Morgan State University, Baltimore, MD 21251, USA.ORCID 0009-0007-8038-5594
Fahmi KhalifaDepartment of Electrical and Computer Engineering, Morgan State University, Baltimore, MD 21251, USA.ORCID 0000-0003-3318-2851
Camille RaginCancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.ORCID 0000-0003-0816-4942
Valerie Odero-MarahDepartment of Biology, Morgan State University, Baltimore, MD 21251, USA.ORCID 0000-0001-7525-4652

Funding

Wastewater surveillance for addressing environmental health disparitiesU54MD013376 · NIMHD · MORGAN STATE UNIVERSITY · PI Timothy J Meeker · 2019 to 2026
$33.5M
NIMHD NIH HHS 2U54MD007590NIMHD NIH HHS U54MD013376
6 · The paper itself

Abstract

RNA In Situ Hybridization (RISH) is a powerful tool for spatial gene expression analysis, yet its quantitative use remains limited by the high cost and inaccessibility of commercial software, particularly in under-resourced settings. This study developed an Artificial Intelligence/Machine Learning (AI/ML)-assisted RISH quantification pipeline to evaluate expression patterns of High Mobility Group AT Hook-2 (

Indexed as

Artificial IntelligenceHMGA2 ProteinProstatic NeoplasmsRNA IsoformsAgedBiomarkers, TumorGene Expression Regulation, NeoplasticHumansIn Situ HybridizationMachine LearningMaleMiddle AgedBiomarkers, TumorHMGA2 ProteinHMGA2 protein, humanRNA IsoformsAIhigh mobility group AT-hook 2isoform-specific gene expressionmachine learning image analysisRNA in situ hybridization quantification

Identifiers

PMID41516076
PMCPMC12785557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.