In one paragraphArticle in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Ricardo F PereiraLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira n° 228, 4050-313 Porto, Portugal.ORCID 0009-0002-1193-002X Catarina Amoedo-LeiteLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira n° 228, 4050-313 Porto, Portugal.ORCID 0000-0002-7556-4826 Sara Gimondi3B's Research Group, I3BS-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Rua Ave 1, Edifício 1 (Sede), Barco, 4805-694 Guimarães, Portugal.
Sara F Vieira3B's Research Group, I3BS-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Rua Ave 1, Edifício 1 (Sede), Barco, 4805-694 Guimarães, Portugal.ORCID 0000-0001-9158-3114 João HandelLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira n° 228, 4050-313 Porto, Portugal.
Andreia PalmeiraLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira n° 228, 4050-313 Porto, Portugal.ORCID 0000-0002-1391-2143 Maria Elizabeth TiritanLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira n° 228, 4050-313 Porto, Portugal.ORCID 0000-0003-3320-730X Madalena M M PintoLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira n° 228, 4050-313 Porto, Portugal.
Nuno M Neves3B's Research Group, I3BS-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Rua Ave 1, Edifício 1 (Sede), Barco, 4805-694 Guimarães, Portugal.ORCID 0000-0003-3041-0687 Helena Ferreira3B's Research Group, I3BS-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Rua Ave 1, Edifício 1 (Sede), Barco, 4805-694 Guimarães, Portugal.ORCID 0000-0002-3770-9393 Carla FernandesLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira n° 228, 4050-313 Porto, Portugal.ORCID 0000-0003-0940-9163 Funding
INSTRUMENTAL ANALYSISZ01CT000014 · CIT · COMPUTER RESEARCH AND TECHNOLOGY · PI WEISS, GEORGE H · 1985 to 2008
$408kFundação para a Ciência e Tecnologia 2023.06754.CEECIND/CP2841/CT0014Fundação para a Ciência e Tecnologia LA/P/0101/2020 (https://doi.org/10.54499/LA/P/0101/2020)Fundação para a Ciência e Tecnologia NORTE-01-0145-FEDER-000039Fundação para a Ciência e Tecnologia PD/BD/135246/2017 and COVID/BD/152012/2021Fundação para a Ciência e Tecnologia PINFRA/22190/2016 (Norte-01-0145-FEDER-022190Fundação para a Ciência e Tecnologia projects PATH (PD/00169/2013), and UID/50026:3B'sFundação para a Ciência e Tecnologia UIDB/04423/2020 (https://doi.org/10.54499/UIDB/04423/2020)Fundação para a Ciência e Tecnologia UIDP/04423/2020 (https://doi.org/10.54499/UIDP/04423/2020)Intramural NIH HHS Z01 CT000014
6 · The paper itselfAbstract
Carboxyxanthones containing carboxylic acid groups linked to lipophilic aromatic rings resemble the key pharmacophoric features of many nonsteroidal anti-inflammatory drugs (NSAIDs). This structural similarity makes them attractive scaffolds for the development of new anti-inflammatory agents. This study describes the production, cytocompatibility, and anti-inflammatory potential of ten carboxyxanthones (
Indexed as
Anti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalXanthonesAnimalsComputer SimulationCyclooxygenase 2DinoprostoneHumansInterleukin-6LipopolysaccharidesMacrophagesMiceMolecular Docking SimulationAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalCyclooxygenase 2DinoprostoneInterleukin-6LipopolysaccharidesXanthonesanti-inflammatory activitycarboxyxanthonescyclooxygenase-2diaryl ether intermediatesdockingdrug discoveryinterleukin 6lipopolysaccharide-stimulated macrophagesprostaglandin E2structure–activity relationship (SAR) analysesxanthone derivatives
Identifiers
PMID41515988
PMCPMC12785596
What OpenQuestion holds
Textmetadata
LicenceCC BY
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