Evidence map›Paper›PMID 41515979›Full record

ReviewInternational journal of molecular sciences2025

MDM2 in Tumor Biology and Cancer Therapy: A Review of Current Clinical Trials.

Francesco Russano, Mattia Sturlese, Luigi Dall'Olmo, Francesco Callegarin, Davide Brugnolo, Paolo Del Fiore, Vittoria Patti, Arianna Purpura, Stefano Moro, Marco Rastrelli and 1 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesco RussanoSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), 35128 Padua, Italy.
Mattia SturleseMolecular Modeling Section, Department of Pharmaceutical and Pharmacological Sciences, University of Padua, 35131 Padua, Italy.ORCID 0000-0003-3944-0313
Luigi Dall'OlmoSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), 35128 Padua, Italy.ORCID 0000-0003-1564-2594
Francesco CallegarinClinical Research Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.ORCID 0009-0000-9594-5178
Davide BrugnoloSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), 35128 Padua, Italy.ORCID 0009-0000-9709-977X
Paolo Del FioreSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), 35128 Padua, Italy.ORCID 0000-0002-2862-8014
Vittoria PattiSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), 35128 Padua, Italy.
Arianna PurpuraSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), 35128 Padua, Italy.
Stefano MoroMolecular Modeling Section, Department of Pharmaceutical and Pharmacological Sciences, University of Padua, 35131 Padua, Italy.ORCID 0000-0002-7514-3802
Marco RastrelliSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), 35128 Padua, Italy.
Simone MocellinSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), 35128 Padua, Italy.ORCID 0000-0002-9433-8445

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Murine Double Minute 2 (

Indexed as

Antineoplastic AgentsNeoplasmsProto-Oncogene Proteins c-mdm2AnimalsClinical Trials as TopicHumansMolecular Targeted TherapyTumor Suppressor Protein p53Antineoplastic AgentsMDM2 protein, humanProto-Oncogene Proteins c-mdm2Tumor Suppressor Protein p53cancer therapyclinical trialdrug developmentMDM2MDM2 inhibitorsp53

Identifiers

PMID41515979
PMCPMC12786238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.