Evidence map›Paper›PMID 41515905›Full record

ArticleInternational journal of molecular sciences2025

First Report of Entrectinib as a Treatment Option for Pure Squamous Cell Carcinoma Harboring

Yan-Jei Tang, Rung-Hsuan Chen, Yung-Shin Lu, Chiao-En Wu

Abstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yan-Jei TangCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-7597-9909
Rung-Hsuan ChenCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Yung-Shin LuCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Chiao-En WuCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-1081-8805

Funding

Chang-Gung Memorial Hospital CMRPG3J0971~3, CMRPVVP0111, CORPVVQ0021, and CMRPVVQ0041 to CEW; CMRPG3P0101 to HJSNational Science and Technology Council 113-2628-B-182-001-MY3 and 113-2811-B-182-024 to CEW
6 · The paper itself

Abstract

Lung cancer remains the leading cause of cancer-related mortality worldwide, with non-small cell lung cancer (NSCLC) accounting for the majority of cases. Among the NSCLC subtypes, squamous cell carcinoma (SCC) is less frequently associated with actionable genetic alterations. Herein, we present the first known case of

Indexed as

BenzamidesCarcinoma, Squamous CellGene RearrangementIndazolesLung NeoplasmsProtein-Tyrosine KinasesProto-Oncogene ProteinsHigh-Throughput Nucleotide SequencingHumansMolecular Targeted TherapyBenzamidesentrectinibIndazolesProtein-Tyrosine KinasesProto-Oncogene ProteinsROS1 protein, humanentrectinibnext-generation sequencingnon-small cell lung cancernon-smokingROS1 rearrangementsquamous cell lung cancer

Identifiers

PMID41515905
PMCPMC12785662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.