Evidence map›Paper›PMID 41515898›Full record

ArticleInternational journal of molecular sciences2025

Plasma Levels of Food-Derived Metabolites as Biomarkers of Parkinson's Disease.

Xiaoxue Dong, Yilong Zheng, Evelyn Ting Ying Tan, Qiao Yang Sun, Bin Xiao, Eng King Tan, Yun-Cheng Wu, Zhi Dong Zhou

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoxue DongDepartment of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.86, Wujin Road, Shanghai 200080, China.
Yilong ZhengSingHealth PGY1 Program, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.
Evelyn Ting Ying TanSchool of Biological Science, Nanyang Technological University, 50 Nanyang Ave, Singapore 639798, Singapore.
Qiao Yang SunDepartment of Neurology, National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore.ORCID 0000-0002-7842-7034
Bin XiaoDepartment of Neurology, National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore.ORCID 0000-0003-2986-4980
Eng King TanDepartment of Neurology, National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore.
Yun-Cheng WuDepartment of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.86, Wujin Road, Shanghai 200080, China.
Zhi Dong ZhouDepartment of Neurology, National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore.ORCID 0000-0003-0251-4163

Funding

National Medical Research Council Clinician Scientist-Individual Research Grants (CS-IRG) (MOH-001091, CIRG23jul-0006)National Medical Research Council HLCA2024 (HLCA24Mar-0019)National Medical Research Council Open Fund-Individual Research Grant (OF-IRG, MOH-001506)National Medical Research Council Open Fund Large Collaborative Grant (MOH-OFLCG24may-0004)National Medical Research Council Singapore Translational Research (STaR) Investigator Award (NMRC/STaR/0030/2018)National Natural Science Foundation of China 82171243SingHealth Singhealth-Duke-NUS AM Position grant
6 · The paper itself

Abstract

Parkinson's disease (PD) is a progressive neurodegenerative disorder shaped by genetic factors such as

Indexed as

BiomarkersParkinson DiseaseAgedAlkaloidsBenzodioxolesCaffeineFemaleHumansLeucine-Rich Repeat Serine-Threonine Protein Kinase-2MalePiperidinesPolyunsaturated AlkamidesTandem Mass SpectrometryAlkaloidsBenzodioxolesBiomarkersCaffeineLeucine-Rich Repeat Serine-Threonine Protein Kinase-2PiperidinespiperinePolyunsaturated Alkamidestrigonellinebiomarkerscaffeinedisease progressionfood-derived metabolitesGBA1 mutationsLRRK2 mutationsparaxanthineParkinson’s diseasepiperinePPMI cohortsitosteryl hexosidetrigonelline

Identifiers

PMID41515898
PMCPMC12785599

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.