Evidence map›Paper›PMID 41515890›Full record

ArticleInternational journal of molecular sciences2025

Quantitative ctDNA Profiling of

Benoist Chibaudel, Elisabeth Carola, Hamid Mekranter, Perrine Goyer, Arnaud Saget, Olivier Oberlin, Hélène Marijon, Hubert Richa, Ida Iurisci, Honorine Gervais and 6 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Clinical and Molecular Correlates of Circulating Tumor Fraction in Patients with Metastatic Pancreatic Ductal Adenocarcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Benoist ChibaudelDepartment of Medical Oncology, Hôpital Franco-Britannique-Fondation Cognacq-Jay, Cancérologie Paris Ouest, 92300 Levallois-Perret, France.ORCID 0000-0003-1279-2044
Elisabeth CarolaDepartment of Medical Oncology, Groupe Hospitalier du Sud de l'Oise, 60100 Creil, France.
Hamid MekranterDepartment of Medical Oncology, Centre Hospitalier François Quesnay, 78200 Mantes La Jolie, France.
Perrine GoyerDigestive Surgery, Cabinet ADN, 75017 Paris, France.
Arnaud SagetDigestive Surgery, Cabinet ADN, 75017 Paris, France.
Olivier OberlinDigestive Surgery, Cabinet ADN, 75017 Paris, France.
Hélène MarijonDepartment of Medical Oncology, Hôpital Franco-Britannique-Fondation Cognacq-Jay, Cancérologie Paris Ouest, 92300 Levallois-Perret, France.
Hubert RichaDepartment of Digestive Surgery, Hôpital Franco-Britannique-Fondation Cognacq-Jay, 92300 Levallois-Perret, France.
Ida IurisciDepartment of Medical Oncology, Hôpital Franco-Britannique-Fondation Cognacq-Jay, Cancérologie Paris Ouest, 92300 Levallois-Perret, France.
Honorine GervaisDepartment of Medical Oncology, Hôpital Franco-Britannique-Fondation Cognacq-Jay, Cancérologie Paris Ouest, 92300 Levallois-Perret, France.
Nathalie Perez-StaubDepartment of Medical Oncology, Hôpital Franco-Britannique-Fondation Cognacq-Jay, Cancérologie Paris Ouest, 92300 Levallois-Perret, France.
Linda DaineseDepartment of Pathology and Molecular Biology, IHP Group-Paris, 92240 Malakoff, France.
Pascal PujolDepartment of Genetic, Centre Hospitalier Universitaire de Montpellier, 34090 Montpellier, France.ORCID 0000-0001-8315-4715
Alain ToledanoDepartment of Radiotherapy, Hartmann Oncology Radiotherapy Group, Cancérologie Paris Ouest, 92300 Levallois-Perret, France.
Jean-Baptiste BachetDepartment of Gastroenterology, Hôpital La Pitié-Salpétrière, 75013 Paris, France.
Aimery de GramontDepartment of Medical Oncology, Hôpital Franco-Britannique-Fondation Cognacq-Jay, Cancérologie Paris Ouest, 92300 Levallois-Perret, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating tumor DNA (ctDNA) analysis offers a non-invasive approach to molecular profiling. While

Indexed as

Biomarkers, TumorCirculating Tumor DNAColorectal NeoplasmsMutationras ProteinsAdultAgedFemaleGene FrequencyHumansMaleMiddle AgedNeoplasm MetastasisPrognosisRetrospective StudiesBiomarkers, TumorCirculating Tumor DNAras Proteinsbiomarkerscirculating tumor DNAcolorectal cancercomprehensive genomic profilingliquid biopsyprecision medicineprognosisRAS mutationsurvival analysisvariant allele frequency

Identifiers

PMID41515890
PMCPMC12785939

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.