Evidence map›Paper›PMID 41515883›Full record

ReviewInternational journal of molecular sciences2025

The RALF-FERONIA Signaling Axis: A Central Hub Integrating Plant Growth, Reproduction, and Stress Responses.

Ekaterina V Zakharova, Larisa I Fedoreyeva

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ekaterina V ZakharovaAll-Russia Research Institute of Agricultural Biotechnology, Timiryazevskaya 42, 127550 Moscow, Russia.ORCID 0000-0002-1067-2543
Larisa I FedoreyevaAll-Russia Research Institute of Agricultural Biotechnology, Timiryazevskaya 42, 127550 Moscow, Russia.ORCID 0000-0003-4601-1496

Funding

Ministry of Science and Higher Education of the Russian Federation FGUM-2025-0003
6 · The paper itself

Abstract

Rapid alkalinization factor (RALF) peptides represent a central class of signaling molecules in plants, regulating processes ranging from fertilization to immune responses. These diverse functions are largely mediated by a conserved receptor complex centered on FERONIA kinase (FER). This review summarizes recent advances positioning the RALF-FER signaling pathway as a major regulatory hub integrating intrinsic and extrinsic signals to coordinate growth, development, and stress adaptation. We examine how this pathway controls the polar growth of root hairs and pollen tubes, orchestrates reproductive barriers and fertilization, and modulates immune and abiotic stress signaling through mechanisms involving ROS, Ca

Indexed as

Arabidopsis ProteinsPhosphotransferasesPlant DevelopmentPlant ProteinsSignal TransductionStress, PhysiologicalGene Expression Regulation, PlantProtein Serine-Threonine KinasesReproductionArabidopsis ProteinsAt3g51550 protein, ArabidopsisPhosphotransferasesPlant ProteinsProtein Serine-Threonine KinasesCrRLK1LFERONIApeptide signalingplant reproductionRALFRALF-FERONIAstress response

Identifiers

PMID41515883
PMCPMC12786044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.