ArticleMolecules (Basel, Switzerland)2026
Poly(levodopa)-Modified β-(1 → 3)-D-Glucan Hydrogel Enriched with Triangle-Shaped Nanoparticles as a Biosafe Matrix with Enhanced Antibacterial Potential.
Anna Michalicha, Vladyslav Vivcharenko, Anna Tomaszewska, Magdalena Kulpa-Greszta, Barbara Budzyńska, Dominika Fila, Judit Buxadera-Palomero, Agnieszka Krawczyńska, Cristina Canal, Dorota Kołodyńska and 2 more
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In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
12 authors.
Anna MichalichaChair and Department of Biochemistry and Biotechnology, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0001-9625-2437 Vladyslav VivcharenkoDepartment of Tissue Engineering and Regenerative Medicine, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0002-1526-686X Anna TomaszewskaFaculty of Biotechnology, Collegium Medicum, University of Rzeszow, Pigonia 1, 35-310 Rzeszow, Poland.ORCID 0000-0003-2548-0568 Magdalena Kulpa-GresztaFaculty of Biotechnology, Collegium Medicum, University of Rzeszow, Pigonia 1, 35-310 Rzeszow, Poland.ORCID 0000-0002-0874-4704 Barbara BudzyńskaIndependent Laboratory of Behavioral Studies, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0001-5917-9285 Dominika FilaDepartment of Inorganic Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University, Maria Curie-Skłodowska Sq. 2, 20-031 Lublin, Poland.ORCID 0000-0001-9807-6166 Judit Buxadera-PalomeroBiomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Engineering and Institute for Research and Innovation in Health (IRIS), Universitat Politècnica de Catalunya-BarcelonaTech (UPC), Av. Eduard Maristany 10-14, 08019 Barcelona, Spain.ORCID 0000-0003-0897-2093 Agnieszka KrawczyńskaFaculty of Materials Science and Engineering, Warsaw University of Technology, 02-507 Warsaw, Poland.ORCID 0000-0001-6007-7091 Cristina CanalBiomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Engineering and Institute for Research and Innovation in Health (IRIS), Universitat Politècnica de Catalunya-BarcelonaTech (UPC), Av. Eduard Maristany 10-14, 08019 Barcelona, Spain.ORCID 0000-0002-3039-7462 Dorota KołodyńskaDepartment of Inorganic Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University, Maria Curie-Skłodowska Sq. 2, 20-031 Lublin, Poland.ORCID 0000-0002-1788-5648 Anna Belcarz-RomaniukChair and Department of Biochemistry and Biotechnology, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0001-9899-5314 Robert PązikFaculty of Biotechnology, Collegium Medicum, University of Rzeszow, Pigonia 1, 35-310 Rzeszow, Poland.ORCID 0000-0002-4662-6688 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Biomaterials derived from natural-origin polymers often lack the desired functionality and additional features, such as antibacterial properties, which could be beneficial in the design of modern wound dressings. Our research aimed to fabricate biosafe antibacterial dressings through the modification of curdlan-based hydrogels with triangle-shaped silver nanoparticles (AgTNPs) and poly(L-DOPA) (PL). The prepared hydrogels, including physicochemical, structural, biological, and antibacterial assessments, were thoroughly characterized. All formulations were confirmed to be non-toxic toward eukaryotic cells. The presence of PL in the hydrogels significantly reduced mortality in the zebrafish larvae model, highlighting the improved biocompatibility of the hydrogels. The three-component hydrogel (CUR-PL-AgT) demonstrated a high antibacterial effectiveness against
Indexed as
Anti-Bacterial Agentsbeta-GlucansHydrogelsMetal NanoparticlesNanoparticlesAnimalsMicrobial Sensitivity TestsPseudomonas aeruginosaSilverStaphylococcus aureusZebrafishAnti-Bacterial Agentsbeta-GlucanscurdlanHydrogelsSilverantimicrobial biomaterialsheat generation effectspoly(L-DOPA)shape-defined nanoparticleswound dressings
Identifiers
PMID41515476
PMCPMC13319943
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