Evidence map›Paper›PMID 41515467›Full record

ArticleMolecules (Basel, Switzerland)2026

Screening of Bioactive Microalgae from Freshwaters, Collected in Hue, Vietnam: Cytotoxic Constituents from

Nguyen Thi Minh Hang, Nguyen Thi Thu Ha, Hoang Duc Manh, Duong Thi Thuy, Hoang Thi Quynh, Nguyen Thi Thu Lien, Nguyen Thi Tu Oanh, Tran Huu Giap, Buu Huu Tai, Doan Thi Mai Huong and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nguyen Thi Minh HangInstitute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 10072, Vietnam.
Nguyen Thi Thu HaInstitute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 10072, Vietnam.
Hoang Duc ManhNational Foundation for Science and Technology Development, Ministry of Science and Technology, 113 Tran Duy Hung, Yen Hoa, Hanoi 10072, Vietnam.
Duong Thi ThuyInstitute of Science and Technology for Energy and Environment, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 10072, Vietnam.
Hoang Thi QuynhInstitute of Science and Technology for Energy and Environment, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 10072, Vietnam.
Nguyen Thi Thu LienInstitute of Applied Research for Science and Technology, University of Sciences, Hue 530000, Vietnam.
Nguyen Thi Tu OanhInstitute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 10072, Vietnam.
Tran Huu GiapInstitute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 10072, Vietnam.
Buu Huu TaiInstitute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 10072, Vietnam.
Doan Thi Mai HuongInstitute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 10072, Vietnam.
Ngo Quoc AnhInstitute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 10072, Vietnam.
Nguyen Xuan NhiemInstitute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 10072, Vietnam.

Funding

Ministry of Science and Technology ĐTĐLCN-76/22
6 · The paper itself

Abstract

BACKGROUND/

objectivesMicroalgae are recognized as prolific producers of bioactive metabolites with pharmaceutical potential. This study aimed to isolate and characterize cytotoxic constituents from selected cytotoxic microalgae, collected in Hue city, Vietnam.

methodsMicroalgal samples were collected from freshwater bodies, morphologically identified, and maintained in laboratory culture. Thirteen strains were successfully isolated and cultivated in BG11, Z8, and BBM media to determine optimal growth conditions. Cytotoxic effects of extracts/compounds were determined using the sulforhodamine B assay on human lung cancer (SK-LU-1) and human liver cancer (HepG2) cell lines. The methanol extract was partitioned with

resultsFrom the phytoplankton samples collected across six freshwater bodies in Hue city, Vietnam, thirteen microalgal strains were successfully isolated and purified under laboratory conditions. These strains were morphologically and taxonomically identified to be

conclusionsThese results highlight the potential of

Indexed as

Antineoplastic AgentsFresh WaterMicroalgaeCell Line, TumorHep G2 CellsHumansMolecular StructureVietnamAntineoplastic Agentscyanobacteriacytotoxic activityDolichospermum smithiiphenolic glycosidesmithioside Asmithioside B

Identifiers

PMID41515467
PMCPMC12787843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.