Evidence map›Paper›PMID 41515463›Full record

ArticleMolecules (Basel, Switzerland)2026

The Use of Benzoin as a Privileged Structure: Synthesis, Characterization, Crystalline Form and an In Vitro Biological Evaluation of 1,2-Diphenyl-2-[1,2,3]triazol-1-yl-ethanol Derivatives.

Noé Martínez-Romero, Mario Valle-Sánchez, Marco A García-Eleno, Carlos A González-González, David Corona-Becerril, Lizbeth Triana-Cruz, Diego Martínez-Otero, María Teresa Ramírez-Apan, David Morales-Morales, Jorge Andrés Ornelas-Guillén and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Highly Selective Coupled COSmall (Weinheim an der Bergstrasse, Germany) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Noé Martínez-RomeroCentro Conjunto de Investigación en Química Sustentable UAEM-UNAM, Universidad Autónoma del Estado de México, Carretera Toluca-Atlacomulco Km 14.5, Toluca 50200, Estado de México, Mexico.ORCID 0009-0009-3655-2425
Mario Valle-SánchezCentro Conjunto de Investigación en Química Sustentable UAEM-UNAM, Universidad Autónoma del Estado de México, Carretera Toluca-Atlacomulco Km 14.5, Toluca 50200, Estado de México, Mexico.ORCID 0000-0001-7415-203X
Marco A García-ElenoCentro Conjunto de Investigación en Química Sustentable UAEM-UNAM, Universidad Autónoma del Estado de México, Carretera Toluca-Atlacomulco Km 14.5, Toluca 50200, Estado de México, Mexico.
Carlos A González-GonzálezFacultad de Química, Universidad Autónoma del Estado de México, Paseo Colon esq. Paseo Tollocan, Toluca 50120, Estado de México, Mexico.
David Corona-BecerrilCentro Conjunto de Investigación en Química Sustentable UAEM-UNAM, Universidad Autónoma del Estado de México, Carretera Toluca-Atlacomulco Km 14.5, Toluca 50200, Estado de México, Mexico.
Lizbeth Triana-CruzCentro Conjunto de Investigación en Química Sustentable UAEM-UNAM, Universidad Autónoma del Estado de México, Carretera Toluca-Atlacomulco Km 14.5, Toluca 50200, Estado de México, Mexico.
Diego Martínez-OteroCentro Conjunto de Investigación en Química Sustentable UAEM-UNAM, Universidad Autónoma del Estado de México, Carretera Toluca-Atlacomulco Km 14.5, Toluca 50200, Estado de México, Mexico.ORCID 0000-0003-0357-6454
María Teresa Ramírez-ApanInstituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior S. N., Ciudad Universitaria, Coyoacán 04510, Ciudad de México, Mexico.
David Morales-MoralesInstituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior S. N., Ciudad Universitaria, Coyoacán 04510, Ciudad de México, Mexico.ORCID 0000-0002-7984-1819
Jorge Andrés Ornelas-GuillénInstituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, Av. Fco. J. Múgica s/n, Morelia 58030, Michoacán, Mexico.ORCID 0009-0006-0511-1844
Erick Cuevas-YañezCentro Conjunto de Investigación en Química Sustentable UAEM-UNAM, Universidad Autónoma del Estado de México, Carretera Toluca-Atlacomulco Km 14.5, Toluca 50200, Estado de México, Mexico.ORCID 0000-0002-9437-637X

Funding

Secretaría de Ciencia, Humanidades, Tecnología e Innovación 1318908
6 · The paper itself

Abstract

A collection of 40 derivatives of 1,2-diphenyl-2-[1,2,3]triazol-1-yl-ethanol was obtained through a sequence of reactions, starting with benzoin as the initial raw material and using the CuAAC reaction as the key step in this process. The structure of a pair of these compounds was ultimately corroborated by single-crystal X-ray diffraction studies, which also reveals important O-H···N interactions. The antimicrobial activity of synthesized 1,2,3-triazoles was assessed against strains that include

Indexed as

Anti-Infective AgentsAntineoplastic AgentsBenzoinTriazolesAnti-Bacterial AgentsCandida albicansCell Line, TumorCell ProliferationCrystallography, X-RayHumansMicrobial Sensitivity TestsMolecular StructureStaphylococcus aureusStructure-Activity RelationshipAnti-Bacterial AgentsAnti-Infective AgentsAntineoplastic AgentsBenzoinTriazoles1,2,3-triazoleantimicrobial activitybenzoinclick chemistrycrystal structurecytotoxic activity

Identifiers

PMID41515463
PMCPMC12787705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.