Evidence map›Paper›PMID 41515353›Full record

ArticleMolecules (Basel, Switzerland)2025

Electrochemical Detection of Levofloxacin Using a Polydopamine-Based Molecular Imprinting Polymer.

Alessandro Lo Presti, Fabricio Nicolas Molinari, Chiara Abate, Enza Fazio, Carmelo Corsaro, Ottavia Giuffrè, Anna Piperno, Giulia Neri, Claudia Foti

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessandro Lo PrestiDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, 31 Viale F. Stagno d'Alcontres, 98166 Messina, Italy.
Fabricio Nicolas MolinariDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, 31 Viale F. Stagno d'Alcontres, 98166 Messina, Italy.ORCID 0000-0002-2132-7155
Chiara AbateDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, 31 Viale F. Stagno d'Alcontres, 98166 Messina, Italy.ORCID 0000-0002-7431-9220
Enza FazioDepartment of Mathematical and Computer Sciences, Physical Science and Earth Science, University of Messina, 31 Viale F. Stagno d'Alcontres, 98166 Messina, Italy.ORCID 0000-0001-9132-7073
Carmelo CorsaroDepartment of Mathematical and Computer Sciences, Physical Science and Earth Science, University of Messina, 31 Viale F. Stagno d'Alcontres, 98166 Messina, Italy.ORCID 0000-0002-1497-8750
Ottavia GiuffrèDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, 31 Viale F. Stagno d'Alcontres, 98166 Messina, Italy.ORCID 0000-0002-8486-8733
Anna PipernoDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, 31 Viale F. Stagno d'Alcontres, 98166 Messina, Italy.ORCID 0000-0001-6004-5196
Giulia NeriDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, 31 Viale F. Stagno d'Alcontres, 98166 Messina, Italy.ORCID 0000-0002-4458-0022
Claudia FotiDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, 31 Viale F. Stagno d'Alcontres, 98166 Messina, Italy.ORCID 0000-0003-2649-7660

Funding

European Union (NextGeneration EU) MUR-PNRR project SAMOTHRACE (ECS00000022)
6 · The paper itself

Abstract

The integration of molecular imprinting technology with electrochemical methods has become fundamental in the development of next-generation sensors. This study explores two different strategies for developing a dopamine-based molecularly imprinted polymer (MIP) for the electrochemical sensing of levofloxacin. In the first case, the MIP is developed by electropolymerization on a screen-printed carbon electrode (SPCE) surface using cyclic voltammetry, while in the second, the MIP is obtained by an oxidation process, and the resulting dispersion is drop-cast on the SPCE surface. The same approach is used for a non-imprinted polymer. The physicochemical properties of the synthesized materials and the surface morphology of the modified electrodes are investigated by several techniques. Differential pulse voltammetry is used to evaluate the performance of the modified electrodes, assessing their linear concentration range, limit of detection, and limit of quantification, together with repeatability and selectivity. MIP-based SPCEs obtained with these two fabrication strategies exhibited comparable imprinting factor values and linear concentration ranges, along with comparable limits of detection and quantification. The MIP-based SPCE obtained by electropolymerization showed greater repeatability, whereas the MIP-based SPCE produced by drop-casting provided higher sensitivity in levofloxacin detection.

Indexed as

Electrochemical TechniquesIndolesLevofloxacinMolecular ImprintingMolecularly Imprinted PolymersPolymersCarbonElectrodesLimit of DetectionCarbonIndolesLevofloxacinMolecularly Imprinted PolymerspolydopaminePolymersdopamineelectrochemical sensorlevofloxacinmolecularly imprinted polymerscreen-printed carbon electrodes

Identifiers

PMID41515353
PMCPMC12787073

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.