Evidence map›Paper›PMID 41515325›Full record

ArticleMolecules (Basel, Switzerland)2025

Synthesis and Application of a Glucoconjugated Organometallic Rhenium Complex as an IR Imaging Probe for Glycolytic Cancer Cells.

Giulia Bononi, Erica Paltrinieri, Serena Fortunato, Gaspare Cicio, Nicola Di Giovanni, Giulia Lencioni, Niccola Funel, Elisa Giovannetti, Carlotta Granchi, Valeria Di Bussolo and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Giulia BononiDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0002-4336-4344
Erica PaltrinieriDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0002-7161-7409
Serena FortunatoDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Gaspare CicioDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0003-4859-2052
Nicola Di GiovanniDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Giulia LencioniCancer Pharmacology Laboratory, AIRC Start-Up Unit, Fondazione Pisana per la Scienza, Via Ferruccio Giovannini, 13, San Giuliano Terme, 56017 Pisa, Italy.ORCID 0009-0008-6521-337X
Niccola FunelUSL Tuscany Northwest Location Lucca, Department of Laboratory Diagnostics, Via Lippi Francesconi, 55100 Lucca, Italy.ORCID 0000-0002-5028-2363
Elisa GiovannettiCancer Pharmacology Laboratory, AIRC Start-Up Unit, Fondazione Pisana per la Scienza, Via Ferruccio Giovannini, 13, San Giuliano Terme, 56017 Pisa, Italy.ORCID 0000-0002-7565-7504
Carlotta GranchiDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0002-5849-0722
Valeria Di BussoloDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0001-6126-9984
Filippo MinutoloDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0002-3312-104X

Funding

European Union - NextGeneration EU through through the Italian Ministry of University and Research PNRR - M4C2-I1.3 Project PE_00000019 "HEAL ITALIA"
6 · The paper itself

Abstract

Current tumor diagnostics rely on fluorodeoxyglucose (FDG)-PET imaging, but FDG's short half-life and high cost limit its widespread use. Infrared (IR) probes are emerging as non-radioactive alternatives to conventional tracers for tissue section and other in vitro imaging applications. Because cells and tissues are relatively free of absorption peaks between 1800 and 2200 cm

Indexed as

Coordination ComplexesGlucoseGlycolysisNeoplasmsOrganometallic CompoundsRheniumCell Line, TumorHumansInfrared RaysCoordination ComplexesGlucoseOrganometallic CompoundsRheniumcancer imagingglucoconjugated rhenium complexesglucoconjugatesinfrared (IR) probesmetal-carbonyl complexesrhenium tricarbonyl complexes

Identifiers

PMID41515325
PMCPMC12786666

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.