ArticleNutrients2026
Conclusions Are Not Supported by the Published Statistical Analysis. Comment on López-Toledo et al. Flaxseed Improves Glucose and Lipid Metabolism in Mexican Subjects with Type 2 Diabetes: A Parallel Randomized Clinical Trial.
Robert W Spitz, Deependra K Thapa, Thirupathi Reddy Mokalla, Wasiuddin Najam, Andrew W Brown, David B Allison
Abstract readComment
In one paragraphArticle in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
6 authors.
Robert W SpitzDepartment of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216, USA.ORCID 0009-0007-4270-6932 Deependra K ThapaDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, IN 47405, USA.ORCID 0000-0002-5689-0837 Thirupathi Reddy MokallaDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, IN 47405, USA.
Wasiuddin NajamDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, IN 47405, USA.ORCID 0000-0001-5867-8883 Andrew W BrownDepartment of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0000-0002-1758-8205 David B AllisonDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, IN 47405, USA.ORCID 0000-0003-3566-9399 Funding
The Role of the Mitochondrion in the Metabolic Stress Response to Burn TraumaP20GM109096 · NIGMS · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI PORTER, CRAIG · 2016 to 2025
$20.7MStrengthening Causal Inference in Behavioral Obesity ResearchR25HL124208 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLISON, DAVID B, BROWN, ANDREW W · 2014 to 2023
$1.8MThe Mathematical Sciences in Obesity ResearchR25DK099080 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAVID B ALLISON, Andrew W Brown · 2013 to 2026
$1.2MNHLBI NIH HHS R25 HL124208NIDDK NIH HHS R25 DK099080NIGMS NIH HHS P20 GM109096
6 · The paper itselfAbstract
López-Toledo et al [...].
Indexed as
Blood GlucoseDiabetes Mellitus, Type 2FlaxLipid MetabolismSeedsHumansMexicoBlood GlucoseDINS errornutritionreproducibilityrigortype I error
Identifiers
PMID41515286
PMCPMC12787444
What OpenQuestion holds
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