Evidence map›Paper›PMID 41515068›Full record

ReviewPlants (Basel, Switzerland)2026

Interaction of 4-Aminobutyrate (GABA) with the Tricarboxylic Acid Cycle in Plants Under Salinity Stress.

Edward J Flaherty, Barry J Shelp

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Metabolomics Analysis of Different Varieties ofFoods (Basel, Switzerland) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Edward J FlahertyDepartment of Plant Agriculture, University of Guelph, Guelph, ON N1G 2W1, Canada.
Barry J ShelpDepartment of Plant Agriculture, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0001-6568-814X

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN/03986-2020
6 · The paper itself

Abstract

The 4-aminobutyrate (GABA) shunt bypasses 2-oxoglutarate dehydrogenase and succinyl-CoA synthetase in the tricarboxylic acid cycle (TCAC) by diverting 2-oxoglutarate to glutamate and generating GABA via glutamate decarboxylase (GAD), whereas polyamine oxidation generates GABA directly from 4-aminobutanal. During salinity stress, the TCAC switches from a cyclic to a non-cyclic mode of operation probably due to the inhibition of two thiamine pyrophosphate-dependent enzymes, 2-oxoglutarate dehydrogenase and pyruvate dehydrogenase, and increases GAD activity via both transcriptional and post-transcriptional (i.e., elevated cytosolic Ca

Indexed as

4-aminobutanal4-aminobutyrateabiotic stressGABAglutamate decarboxylasemetabolismorganic acidspolyaminessalinitytricarboxylic acid cycle

Identifiers

PMID41515068
PMCPMC12787904

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.