Evidence map›Paper›PMID 41514861›Full record

ArticleBiology2025

Allostery-Driven Substrate Gating in the Chlorothalonil Dehalogenase from

Grayson Gerlich, Judith Klein-Seetharaman, Richard C Holz

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Grayson GerlichQuantitative Biosciences and Engineering Program, Colorado School of Mines, Golden, CO 80401, USA.ORCID 0000-0002-8413-8984
Judith Klein-SeetharamanSchool of Molecular Sciences, Arizona State University, Phoenix, AZ 85004, USA.ORCID 0000-0002-4892-6828
Richard C HolzDepartment of Chemistry, Colorado School of Mines, Golden, CO 80401, USA.ORCID 0000-0001-6093-2799

Funding

National Science Foundation CHE-2452699
6 · The paper itself

Abstract

The catalytic mechanism of the Zn(II)-dependent chlorothalonil dehalogenase from

Indexed as

bioremediationchlorinated aromatic hydrocarbonschlorothalonildechlorinationdehalogenasedockingenzyme catalysisenzyme mechanismmetalloenzymemolecular dynamicszinc

Identifiers

PMID41514861
PMCPMC12784990

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.