Evidence map›Paper›PMID 41514817›Full record

ReviewAnimals : an open access journal from MDPI2026

Phosphorus Metabolism and Function in Ruminants: Current Knowledge.

Beata Abramowicz, Ewa Tomaszewska, Oliwia Brzezińska, Karolina Kłos, Miroslav Urosevic, Łukasz Kurek

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Beata AbramowiczDepartment and Clinic of Animal Internal Diseases, University of Life Sciences in Lublin, Akademicka 13, 20-912 Lublin, Poland.ORCID 0000-0003-4801-3073
Ewa TomaszewskaDepartment of Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Akademicka 13, 20-912 Lublin, Poland.ORCID 0000-0002-4442-2833
Oliwia BrzezińskaDepartment and Clinic of Animal Internal Diseases, University of Life Sciences in Lublin, Akademicka 13, 20-912 Lublin, Poland.ORCID 0009-0008-4935-3233
Karolina KłosFaculty of Veterinary Medicine, University of Life Sciences in Lublin, Akademicka 13, 20-912 Lublin, Poland.
Miroslav UrosevicDepartment of Animal Science, Faculty of Agriculture, University of Novi Sad, Trg D. Obradovića 8, 21000 Novi Sad, Serbia.
Łukasz KurekDepartment and Clinic of Animal Internal Diseases, University of Life Sciences in Lublin, Akademicka 13, 20-912 Lublin, Poland.ORCID 0000-0001-5408-6610

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphorus (P) is a key macromineral essential for numerous physiological processes, including energy metabolism, skeletal mineralization, and cellular signaling. In dairy cattle, its homeostasis is tightly regulated by parathyroid hormone, calcitriol, and fibroblast growth factor 23 (FGF23). Phosphorus deficiency is common during the transition period and is associated with reduced milk yield, anemia, muscle weakness, and immunosuppression in severe or prolonged cases. This review summarizes the current understanding of phosphorus metabolism in ruminants, emphasizing differences from monogastric species, hormonal regulation, and the clinical manifestations of deficiency. Particular attention is given to postpartum hypophosphatemia, its relationship with acute-phase proteins, and the pathogenesis of postpartum hemoglobinuria and recumbency. The review also discusses diagnostic methods for assessing phosphorus status, recent findings on FGF23 physiology in cattle, and including demonstrated effects of phosphorus imbalance on periparturient immune suppression and increased environmental phosphorus losses through manure. Maintaining optimal phosphorus nutrition is crucial for bovine health, productivity, and reduction in environmental phosphorus losses.

Indexed as

acute-phase proteinsdairy cowsFGF23mineral metabolismphosphorus deficiencypostpartum disorders

Identifiers

PMID41514817
PMCPMC12784716

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.