Neoadjuvant Chemotherapy for Oropharyngeal Cancer Treatment De-Escalation: From Historical Failures to Contemporary HPV-Driven Paradigms.

Alvaro Sanabria, Juan P Rodrigo, Anna Luíza Damaceno Araújo, Luiz P Kowalski

Abstract readReview

In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alvaro SanabriaDepartment of Surgery, School of Medicine, Universidad de Antioquia-Hospital Universitario San Vicente Fundacion-Clinica Somer-Clinica Las Vegas Grupo Quironsalud, Medellín 050010, Colombia.ORCID 0000-0002-5563-8840

Juan P RodrigoDepartment of Otolaryngology, ISPA (Instituto de Investigacion Santiara del Principado de Asturias), IUOPA (Instituto Universitario de Oncología del Principado de Asturias), CIBERONC (Centro de Investigación Biomédica en Red de Cáncer), Hospital Universitario Central de Asturias, University of Oviedo, 33011 Oviedo, Spain.ORCID 0000-0003-3063-0890

Anna Luíza Damaceno AraújoHead and Neck Surgery Department, University of São Paulo Medical School, São Paulo 05403-000, São Paulo, Brazil.ORCID 0000-0002-3725-8051

Luiz P KowalskiHead and Neck Surgery Department, University of São Paulo Medical School, São Paulo 05403-000, São Paulo, Brazil.ORCID 0000-0002-0481-156X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

de-escalationHPV-positive OPSCCimmunotherapyneoadjuvant chemotherapyorgan preservationoropharyngeal squamous cell carcinomatransoral surgery

Identifiers

PMID41514536

DOI10.3390/cancers18010023

PMCPMC12784758

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.