Evidence map›Paper›PMID 41514353›Full record

ArticleBMC nutrition2026

Effects of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and forest bathing in improving cognitive and metabolic health among hypertensive older adults: a feasibility randomised controlled trial.

Queenie Pui Sze Law, Katherine Ka Yin Yau, Stefanos Tyrovolas, Rick Yiu Cho Kwan

Registry-linked trialAbstract read
In one paragraph

Article in BMC nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05342896 (Effect of Mediterranean-DASH Intervention for Neurodegenerative Delay), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05342896 nacompletednot on this map

Effect of Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Plus Forest Bathing (FB) on Blood Pressure and Cognitive Health for Those Who Are Aged 50 and Above With Hypertension

TypeinterventionalSponsorHong Kong Metropolitan UniversityRan2021 to 2023Enrolled48ConditionsHigh Blood PressureArmsMIND diet, Mind diet plus Forest Bathing
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Experiences of Nature Through Immersive Virtual Reality Among People with Type 2 Diabetes Mellitus.International journal of environmental research and public health · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Queenie Pui Sze LawSchool of Nursing and Health Sciences, Hong Kong Metropolitan University, Hong Kong SAR, China.ORCID http://orcid.org/0000-0002-1388-0372
Katherine Ka Yin YauSchool of Nursing, Tung Wah College, Hong Kong SAR, China. kyyau@twc.edu.hk.ORCID http://orcid.org/0000-0001-5502-1552
Stefanos TyrovolasDepartment of Nutrition and Food Studies, George Mason University, Fairfax, USA.ORCID http://orcid.org/0000-0003-4797-7743
Rick Yiu Cho KwanSchool of Nursing, Tung Wah College, Hong Kong SAR, China.ORCID http://orcid.org/0000-0002-4332-780X

Funding

Hong Kong Metropolitan University HE-NHS2021/02
6 · The paper itself

Abstract

backgroundThis study aimed to assess the feasibility of the protocol, including recruitment rate, intervention adherence, dropout rate, the occurrence of adverse effects and feedback from participants. This study also sought to evaluate the effects of two interventions—MIND + FB (Mediterranean-DASH Intervention for Neurodegenerative Delay diet combined with forest bathing) and MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay diet only)—on clinical outcomes, including cognitive function, metabolic health markers, and adherence to the MIND diet, both immediately post-intervention and three months post-intervention. It was hypothesized that both intervention groups would show significant within-group improvements in outcomes, while the control group would not.

methodsA three-parallel-group, single-blinded randomized controlled trial was conducted with 48 participants (aged ≥ 60 years) randomized into MIND + FB (n = 16), MIND (n = 16), and control (n = 16) groups. The outcome assessor was blinded, while the participants and interventionist were not blinded to the group assignment. The MIND + FB group received eight sessions over three months (four nutritional counseling and four forest therapy sessions), the MIND group received four nutritional counseling sessions, and the control group received usual care. Data were collected at baseline (T0), immediately post-intervention (T1), and three months post-intervention (T2). The primary aim was to test the feasibility of the study. The secondary outcomes included cognitive function, metabolic health markers and MIND diet adherence.

resultsThe recruitment rate was 60%, with high adherence (MIND: 97%, MIND + FB: 95%) and a 4.2% dropout rate. No significant adverse effects were reported. Both MIND + FB and MIND groups showed significant within-group improvements in cognitive function with a larger effect size in MIND + FB (Kendall’s W = 0.619). The MIND + FB group also demonstrated significant reductions in fasting blood glucose (Kendall’s W = 0.279)) and waist circumference (Kendall’s W = 0.382)). Improved MIND diet adherence was observed in the MIND group (Kendall’s W = 0.256). Between-group comparisons showed significant cognitive function improvements in both intervention groups versus control.

conclusionsThe MIND + FB intervention may enhance cognitive function and metabolic health in older adults with hypertension, potentially offering greater benefits than the MIND diet alone. While MIND alone promotes better diet adherence, the dose-response effects on health outcomes remain unclear. Future studies should refine behavioural strategies to enhance adherence and identify the most effective components. A larger trial is recommended to confirm these findings and address current study limitations.

trial registrationClinialTrials.gov registration number: NCT05342896. Registered on 3rd Jan 2021. https://clinicaltrials.gov/study/NCT05342896 .

Indexed as

Cognitive healthForest bathingHypertensive older adultsMediterranean–DASH intervention for neurodegenerative delay (MIND) dietMetabolic health

Identifiers

PMID41514353
PMCPMC12882264

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.