ArticleBMC geriatrics2026
Association between lifestyle habits and central sensitization in community-dwelling older adults in Japan: a cross-sectional analysis from the Otassha study.
Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDisruptions in daily lifestyle habits are associated with various health issues, including chronic pain. Central sensitization, characterized by heightened responsiveness of the central nervous system, plays a key role in pain perception. However, its relationship with modifiable lifestyle habits such as physical activity, smoking, and alcohol consumption remains unclear. This study aimed to examine the association between these lifestyle factors and central sensitization in community-dwelling older adults in Japan.
methodsThis cross-sectional study used data from 574 adults aged 65–84 years participating in the 2023 Otassha Study. Central sensitization was assessed using the Japanese version of the Central Sensitization Inventory (CSI). Information on lifestyle habits, including physical activity, smoking, and alcohol consumption, was collected via self-administered questionnaires. Regression and ANOVA analyses were conducted to evaluate associations between lifestyle factors and central sensitization scores, adjusting for age and sex.
resultsModerate physical activity was significantly associated with lower CSI scores (adjusted coefficient = − 1.83, 95% CI = − 3.41 to − 0.25, p = 0.02). Moderate physical activity showed a marginal overall association with lower CSI scores (ANCOVA p = 0.05). While the highest activity quartile exhibited significantly lower CSI levels compared with inactivity (p < 0.01), no significant differences were observed for the lower quartiles, and the linear trend across quartiles was not significant (p for trend = 0.16). No significant associations were found for vigorous activity, walking activity, smoking exposure, or alcohol consumption.
conclusionsModerate physical activity showed a marginal association with lower levels of central sensitization, with only the highest activity quartile demonstrating significantly lower CSI scores. Although a clear dose–response trend was not observed, these findings suggest that higher levels of moderate activity may contribute to reduced sensitization in older adults. Longitudinal studies are needed to clarify causal relationships.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.