ArticleBMC endocrine disorders2026
Mean arterial pressure is not associated with type 2 diabetes mellitus in Japan: a secondary retrospective analysis.
Article in BMC endocrine disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe association between mean arterial pressure (MAP) and diabetes has been explored in some studies; however, the results have been controversial.
methodsThis longitudinal cohort study included 8,430 males and 7,034 females. The follow-up period lasted for 13 years, from 1994 to 2016. We categorized the participants according to the MAP quartiles. We investigated the association between MAP and type 2 diabetes mellitus (T2DM) and expressed it as hazard ratios (HRs) with 95% confidence intervals (CIs) after adjusting for potential confounders.
resultsAfter multivariate adjustment, we found that MAP was not a risk factor for incident T2DM using Cox regression analysis. The HR at the highest quartile of MAP was 1.10 (0.75, 1.61), p = 0.6363, compared to the lowest quartile of MAP. In the subgroup analysis, there was no interaction between MAP and the development of T2DM.
conclusionsMAP was not associated with the incidence of T2DM in Japan. CLINICAL TRIAL NUMBER: Not applicable.
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