Evidence map›Paper›PMID 41514247›Full record

Trial reportBMC complementary medicine and therapies2026

Effectiveness of tuina and physiotherapy to manage pain for patients with chronic low back pain: a pragmatic randomized clinical trial.

Ia Choo Celia Tan, Hao En Matthew Wong, Fan Qiao, Wei Min Chong, Chee Cheong Reuben Soh, Chin Ee Ho, Kwok Chee Philip Cheong, Li Tat John Chen, Pao Ann Bong, Ing Hian Niklas Seet and 8 more

Abstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in BMC complementary medicine and therapies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ia Choo Celia TanDepartment of Physiotherapy, Singapore General Hospital, Singapore, Singapore. celia.tan.i.c@singhealth.com.sg.
Hao En Matthew WongCurtin School of Allied Health, Curtin University, Curtin, Australia.
Fan QiaoCentre for Quantitative Medicine, Duke-NUS, Singapore, Singapore.
Wei Min ChongDepartment of Physiotherapy, Singapore General Hospital, Singapore, Singapore.
Chee Cheong Reuben SohDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.
Chin Ee HoAcademy of Chinese Medicine, Singapore, Singapore.
Kwok Chee Philip CheongDepartment of Physiotherapy, Singapore General Hospital, Singapore, Singapore.
Li Tat John ChenDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.
Pao Ann BongAcademy of Chinese Medicine, Singapore, Singapore.
Ing Hian Niklas SeetDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.
Xiu Wen LimAcademy of Chinese Medicine, Singapore, Singapore.
Qing Yu MaSchool of Traditional Chinese Medicine, Jinan University, Guangzhou, China.
Xuan ZhouSchool of Traditional Chinese Medicine, Jinan University, Guangzhou, China.
Long Bin ShenSchool of Traditional Chinese Medicine, Jinan University, Guangzhou, China.
Juan YangDepartment of Medicine, Mayo Clinic, Rochester , MN, United States.
Jia Xu ChenSchool of Traditional Chinese Medicine, Jinan University, Guangzhou, China.
Brent A BauerDepartment of Medicine, Mayo Clinic, Rochester , MN, United States.
Boon Keng TayDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.

Funding

HEAD foundation GRTHF0000101
6 · The paper itself

Abstract

backgroundChronic non-specific low back pain lacks a defined pathoanatomical cause, leading to diverse treatment methods including physiotherapy and complementary alternative medicine techniques such as Tuina. This study aimed to evaluate the effectiveness of Tuina for managing chronic non-specific low back pain by comparing it to physiotherapy and a combination of physiotherapy and Tuina.

methodsIn this randomized, parallel-controlled, single-blind trial, 204 participants aged 21 to 75 with chronic non-specific low back pain were randomly assigned to physiotherapy, Tuina, or combined therapy. Pain intensity and quality of life were measured with the visual analog scale, 36-Item Short Form Survey and the Oswestry Disability Index, alongside trunk range of motion. Outcomes were assessed at baseline, two months, and five months. Data were analyzed using analysis of variance for within- and between-group comparisons, and post-hoc tests were applied to between-group comparisons.

resultsAfter two months, all groups had significant improvement in pain scores. Tuina was only significantly better than the combination treatment for reducing pain (p = 0.021; mean difference = - 1.04 [95% CI - 1.85 to - 0.23], Cohen's d = - 0.41). However, no significant difference was observed between Tuina and combined treatment against physiotherapy. Pain scores were not significantly different at five months in all groups. The physiotherapy (p = 0.019; mean difference = - 5.28 [95% CI - 9.44 to - 1.11], d = - 0.44) and combined (p = 0.028; mean difference = 5.59 [95% CI 1.17 to 10.01], d = 0.42) groups showed a significant reduction in Oswestry Disability Index scores compared to Tuina at five months. The combined group had significantly greater 36-Item Short-Form Survey than Tuina (p = 0.012; mean difference = - 71.15 [95% CI - 118.23 to - 24.06], d = - 0.47), but not significantly greater than physiotherapy.

conclusionsAll treatment groups demonstrated improved outcomes post-intervention and at five months. Between-group differences in improvement were significant only for Oswestry Disability Index and 36-Item Short-Form Survey scores at five months. Pain scores showed no significant superiority of physiotherapy over Tuina and combined therapy (d < 0.2), indicating potential use of Tuina in chronic non-specific low back pain management. TRIALS REGISTRATION: ChiMCTR2000004087.  URL: https://www.chictr.org.cn/showprojEN.html?proj=62614 .  Date of Registration: 27 November 2020.

Indexed as

Chronic PainLow Back PainMassagePhysical Therapy ModalitiesAdultAgedCombined Modality TherapyFemaleHumansMaleMiddle AgedPain MeasurementQuality of LifeSingle-Blind MethodYoung AdultChronic low back painOutcome measuresPhysiotherapyTuina

Identifiers

PMID41514247
PMCPMC12882237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.