Evidence map›Paper›PMID 41514242›Full record

SynthesisBMC public health2026

The impact of alcohol consumption on stroke prognosis: a systematic review and meta-analysis.

Wenying Wu, Tiansheng Zhao, Li Gao, Teng Fan, Le Tian, Xiaomei Wu

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenying Wu *Department of Interventional Surgery, The First Hospital of China Medical University, Shenyang, 110001, China.
Tiansheng Zhao *Department of Clinical Epidemiology and Center of Evidence-Based Medicine, The First Hospital of China Medical University, Shenyang, 110001, China.
Li GaoDalian Center for Disease Control and Prevention, Dalian, 116035, China.
Teng FanDepartment of Clinical Epidemiology and Center of Evidence-Based Medicine, The First Hospital of China Medical University, Shenyang, 110001, China.
Le TianDepartment of Clinical Epidemiology and Center of Evidence-Based Medicine, The First Hospital of China Medical University, Shenyang, 110001, China.
Xiaomei WuDepartment of Clinical Epidemiology and Center of Evidence-Based Medicine, The First Hospital of China Medical University, Shenyang, 110001, China. xiaomeiwu@cmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStroke imposes a substantial global burden. Alcohol consumption is an important and potentially modifiable risk factor, yet its impact on stroke prognosis across different follow-up periods and stroke types remains inconsistent across studies. This study aimed to systematically evaluate the association between alcohol consumption and stroke prognosis, across various follow-up durations and stroke subtypes.

methodsWe systematically searched multiple databases, including PubMed, Web of Science, Embase and others, for relevant studies published from inception to January 2024. we included 58 studies and evaluated their methodological quality using the Newcastle-Ottawa Scale (NOS). Given the substantial heterogeneity among studies, we employed a random-effects model for the meta-analysis.

resultsAlcohol consumption significantly impacts stroke prognosis across various follow-up periods and stroke types. At short-term follow-up, it elevates the risk of poor prognosis in stroke patients (OR 1.62; 95% CI 1.32–1.99). In short- to medium-term follow-up, alcohol consumption is associated with increased risks of stroke recurrence (OR 1.40; 95% CI 1.10–1.78) and poor prognosis (OR 1.74; 95% CI 1.21–2.49). Long-term follow-up reveals a heightened risk of death in stroke patients who consume alcohol (OR 5.14; 95% CI 1.96–13.49). When categorizing strokes into ischemic and hemorrhagic types, alcohol consumption poses significant risks. It increases the risk of poor prognosis in ischemic stroke patients (OR 1.51; 95% CI 1.23–1.86), while also raising the risk of death (OR 1.77; 95% CI 1.26–2.48) and poor prognosis in patients with hemorrhagic stroke (OR 1.88; 95% CI 1.22–2.91).

conclusionsAlcohol consumption was associated with an elevated relative risk of mortality, recurrence, or poor prognosis in stroke patients across different stroke types and during specific follow-up periods. Future studies should more fully explore the effect of alcohol consumption on stroke prognosis in different populations and under different regions.

Indexed as

Alcohol DrinkingStrokeHumansPrognosisRisk FactorsAlcohol consumptionMeta-analysisPrognosisStroke

Identifiers

PMID41514242
PMCPMC12882396

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.