Evidence map›Paper›PMID 41513987›Full record

ArticleNature biomedical engineering2026

Wireless and bioresorbable triboelectric nerve block system for postoperative pain control.

Young-Jun Kim, So-Hee Kim, Byung-Joon Park, Jinyoung Jeon, Donghyeon Kang, Youngwook Chung, Joon-Ha Hwang, Hong-Joon Yoon, Kyu Hyoung Lee, Byung-Ok Choi and 1 more

Abstract read
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In one paragraph

Article in Nature biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Young-Jun Kim *Center for Human-oriented Triboelectric Energy Harvesting, Yonsei University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-9103-7065
So-Hee Kim *Center for Human-oriented Triboelectric Energy Harvesting, Yonsei University, Seoul, Republic of Korea.
Byung-Joon Park *Center for Human-oriented Triboelectric Energy Harvesting, Yonsei University, Seoul, Republic of Korea.
Jinyoung JeonCenter for Human-oriented Triboelectric Energy Harvesting, Yonsei University, Seoul, Republic of Korea.
Donghyeon KangCenter for Human-oriented Triboelectric Energy Harvesting, Yonsei University, Seoul, Republic of Korea.
Youngwook ChungSchool of Advanced Materials Science and Engineering, Sungkyunkwan University, Suwon, Republic of Korea.
Joon-Ha HwangSchool of Advanced Materials Science and Engineering, Sungkyunkwan University, Suwon, Republic of Korea.
Hong-Joon YoonDepartment of Electronic Engineering, Gachon University, Seongnam-si, Republic of Korea.ORCID http://orcid.org/0000-0002-5668-3192
Kyu Hyoung LeeDepartment of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea. khlee2018@yonsei.ac.kr.
Byung-Ok ChoiDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. bochoi@skku.edu.
Sang-Woo KimCenter for Human-oriented Triboelectric Energy Harvesting, Yonsei University, Seoul, Republic of Korea. kimsw1@yonsei.ac.kr.ORCID http://orcid.org/0000-0002-0079-5806

Funding

Ministry of Health and Welfare (Ministry of Health, Welfare and Family Affairs) HR22C1363, HX23C1756National Research Foundation of Korea (NRF) 2022R1A3B1078291, 2020R1A5A1019131
6 · The paper itself

Abstract

Amidst the chronic issue of opioid misuse, finding an alternative to pharmaceutical pain control following surgical interventions stands as a major hurdle. Conventional non-pharmacological pain control technologies often rely on rigid stimulators linking internal and external body components, thereby imposing nerve burden and additional interventions for the removal. Here we introduce a bioresorbable triboelectric nerve cuff activated via ultrasounds for pain control. The targeted nerves are enveloped around polymers with opposite triboelectric properties that vibrate upon ultrasound stimulation, generating an alternating triboelectric field parallel to the nerve for pain modulation. In vivo testing in rat and porcine models demonstrates that the fully implanted neurostimulator exerts no discernible impact on gait and yields immediate pain relief. Application of the implant until full resorbing caused no adverse effects in the nerve or surrounding muscle tissue, and behavioural analysis confirmed its effective pain control. The implantable pain control system might offer a drug-free alternative to pain management strategies, helping prevent drug abuse.

Identifiers

PMID41513987

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.