ArticleCommunications medicine2026
Pink noise reduces impact of traffic noise on sleep and the blood metabolome: a cross-over pilot study.
Article in Communications medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05319262 (Metabolic and Cognitive Consequences of Noise-induced Sleep Disturbance), which is not on this map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Metabolic and Cognitive Consequences of Noise-induced Sleep Disturbance
Who cites it
2 citing papers in PubMed.
- The impact of sound intervention on sleep quality and stress levels in college students: a randomized controlled trial.Frontiers in psychology · 2026Article
- Physical factor therapies for insomnia: a narrative review of mechanisms, clinical evidence, and phenotype-guided applications.Frontiers in psychiatry · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundEpidemiological studies show associations between chronic noise exposure and disease, but the biological pathways remain poorly understood. In this explorative pilot study, we investigate the mechanisms that may link sleep disruption by environmental noise with disease, and the efficacy of a non-pharmacological intervention to mitigate these effects.
methodsWe conducted a cross-over trial (ClinicalTrials.gov: NCT05319262; 2022-03-09) where N = 12 healthy individuals slept for five consecutive nights in acoustically isolated bedrooms. Nights included one familiarisation night; one quiet baseline night; one night with road, rail and air traffic noise of levels 45-65 dB L
resultsHere we show that discrete traffic noise events induced acute elevations of the odds ratio product, indicating acute sleep fragmentation, even while total sleep time and overall sleep macrostructure were preserved. Traffic noise is further associated with significant elevations in concentrations of leucine, lactic acid, and acetone relative to quiet control. Sleep and metabolic disturbances by traffic noise are attenuated when pink noise is played continuously throughout the night.
conclusionsNoise-induced sleep fragmentation is followed by changes in metabolic processes that in the long-term may be precursors for cardiometabolic disorders. Masking of traffic noise by continuous, neutral sound may mitigate acute physiological sleep disturbance and downstream metabolic effects. These results should be interpreted cautiously, given the limited sample size and subject homogeneity.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.