Evidence map›Paper›PMID 41513874›Full record

Trial reportClinical oral investigations2026

Postoperative pain and quality of life after the use of different endodontic sealers in asymptomatic molars: a randomized clinical trial.

Patrícia Santos Oliveira, Meire Coelho Ferreira, Natália Gomes de Paula, Wallace Vieira Mendes, Thieny Gouveia Dos Santos, Giulio Gavini, Leonardo Hunaldo Dos Santos, Suellen Linares Lima, Renata Grazziotin-Soares, Ceci Nunes Carvalho

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Patrícia Santos OliveiraDentistry Postgraduate Program, University Ceuma, R. Josué Montello, 1, Renascença II, São Luís, Maranhão, 65075-120, Brazil.
Meire Coelho FerreiraDentistry Postgraduate Program, University Ceuma, R. Josué Montello, 1, Renascença II, São Luís, Maranhão, 65075-120, Brazil.
Natália Gomes de PaulaDentistry Postgraduate Program, University Ceuma, R. Josué Montello, 1, Renascença II, São Luís, Maranhão, 65075-120, Brazil.
Wallace Vieira MendesDentistry Postgraduate Program, University Ceuma, R. Josué Montello, 1, Renascença II, São Luís, Maranhão, 65075-120, Brazil.
Thieny Gouveia Dos SantosDentistry Postgraduate Program, University Ceuma, R. Josué Montello, 1, Renascença II, São Luís, Maranhão, 65075-120, Brazil.
Giulio GaviniDepartment of Restorative Dentistry, School of Dentistry, University of São Paulo (FOUSP), Av. Lineu Prestes, 2227, São Paulo, 05508-000, Brazil.
Leonardo Hunaldo Dos SantosHealth and Technology Postgraduate Program, Federal University of Maranhão (UFMA), R. Urbano Santos Street, Imperatriz, 65900-410, Maranhão, Brazil.
Suellen Linares LimaDentistry Postgraduate Program, University Ceuma, R. Josué Montello, 1, Renascença II, São Luís, Maranhão, 65075-120, Brazil.
Renata Grazziotin-SoaresDivision of Endodontics, Dept. of Oral Biological and Medical Sciences, Faculty of Dentistry University of British Columbia, UBC Vancouver, Canada.
Ceci Nunes CarvalhoDentistry Postgraduate Program, University Ceuma, R. Josué Montello, 1, Renascença II, São Luís, Maranhão, 65075-120, Brazil. ceci.carvalho@ceuma.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare postoperative pain intensity and incidence after root canal obturation using AH Plus or EndoSequence BC in asymptomatic molars. MATERIALS AND

methodsThis randomized clinical trial included 152 patients and was conducted in accordance with CONSORT guidelines. Teeth were randomly allocated according to the sealer used. Postoperative pain was assessed using validated pain scales at 6, 12, and 24 h, and at 2 and 3 days after obturation. Quality of life was evaluated using the OHIP-14 questionnaire. Bite sensitivity and analgesic intake were also recorded.

resultsPostoperative pain intensity was very low in both groups at all time points. The AH Plus group showed slightly higher pain intensity within the first 24 h compared with the BC sealer group (p < 0.05). No differences were observed between groups regarding pain incidence, bite sensitivity, or impact on quality of life (p > 0.05). Analgesic intake was higher in the AH Plus group. A weak positive correlation was observed between pain intensity and functional limitation domains of the OHIP-14 (physical disability and social impairment).

conclusionsOverall, both sealers resulted in very low postoperative pain. Although AH Plus showed slightly higher pain intensity compared with BC, both sealers demonstrated a similar risk of pain and comparable impact on quality of life. CLINICAL RELEVANCE: Postoperative pain after root canal obturation was minimal with both AH Plus and EndoSequence BC sealers. Minor differences in pain intensity were observed during the early postoperative period, with a slightly faster reduction in pain reported for EndoSequence BC, and no differences in pain risk or impact on quality of life.

Indexed as

MolarPostoperative PainQuality of LifeRoot Canal Filling MaterialsRoot Canal ObturationAdultEpoxy ResinsFemaleHumansMaleMiddle AgedPain MeasurementTreatment OutcomeEpoxy ResinsRoot Canal Filling MaterialsEndodonticsEndodontic sealerObturationPostoperative painQuality of lifeRandomized clinical trial

Identifiers

PMID41513874
PMCPMC12789152

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.