Evidence map›Paper›PMID 41513835›Full record

ArticleInternational journal of colorectal disease2026

The Levator Hiatus Area detected by 3D-TPUS as an indicator of rectal prolapse severity.

Danqi Shao, Jianping Qiu, Junli Yu, Xiangwen Diao, Dan Su, Guangjian Liu

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Article in International journal of colorectal disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Danqi Shao *Department of Ultrasonography, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Jianping Qiu *Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Junli Yu *Department of Ultrasonography, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Xiangwen DiaoDepartment of Emergency, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Dan SuBiomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China. sudan3@mail.sysu.edu.cn.
Guangjian LiuDepartment of Ultrasonography, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China. liugj@mail.sysu.edu.cn.

Funding

Guangdong Provincial Clinical Medical Research Center for Digestive System Diseases 2020B1111170004
6 · The paper itself

Abstract

purposeRectal prolapse (RP) is a clinically significant condition with vaginal delivery as a major risk factor, especially in elderly females, needs precise evaluation for guiding treatment. Given the limitations of current diagnostic methods in terms of convenience, this study aims to develop an improved measure for RP.

methodsA retrospective analysis of 181 female patients undergoing both dynamic three-dimensional transperineal ultrasound (3D-TPUS) and radiographic (X-ray or MRI) defecography (X-ray and MRI) was conducted to investigate the correlation between 3D-TPUS parameters and RP severity.

resultsRelative to mild RP cases, severe RP patients were older, had heavier neonatal birth weight, and less nulliparous individuals. Significant differences in severe RP cases were demonstrated by 3D-TPUS quantification, greater levator hiatal area enlargement (LHA), increased bladder neck descent (BND), and deeper rectal ampulla position (RAP) compared to mild cases. Significant predictors of severe RP identified by univariable logistic regression included age, vaginal parity, RAP, and LHA. Multivariable logistic regression analysis exhibited that age and LHA during Valsalva were the most influential indicators of severe RP. Receiver operating characteristic (ROC) curve analysis revealed that an LHA ≥ 17.5 cm

conclusionsDynamic 3D-TPUS-measured LHA associated with with RP severity and could serve as a quantifiable marker for pelvic floor dysfunction in RP. This study introduces an adjunctive indicator for the severity of RP, improving diagnostic convenience and patient management.

Indexed as

Imaging, Three-DimensionalPelvic FloorRectal ProlapseAdultAgedDefecographyFemaleHumansMagnetic Resonance ImagingMiddle AgedMultivariate AnalysisROC CurveSeverity of Illness IndexUltrasonographyDiagnostic imagingDynamic three-dimensional transperineal ultrasoundLevator hiatal area enlargementProlapse severityRectal prolapse

Identifiers

PMID41513835
PMCPMC12789222

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.