ArticleScientific reports2026
A prediction model for bronchoalveolar lavage in children with Mycoplasma pneumoniae pneumonia and consolidation.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- MiR-128-3p serves as a diagnostic biomarker in pediatric Mycoplasma pneumoniae pneumonia.BMC pulmonary medicine · 2026Article
- Immunopathogenesis, molecular phenotyping, and host-directed interventions for severe pediatricFrontiers in cellular and infection microbiology · 2026Review
- Research progress on the mechanisms of mucus retention after mycoplasma pneumoniae infection.Frontiers in cellular and infection microbiology · 2026Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To identify risk factors associated with the necessity of bronchoalveolar lavage (BAL) in children with Mycoplasma pneumoniae pneumonia (MPP) and pulmonary consolidation, and to develop and validate a predictive model to support clinical decision-making. A retrospective study was conducted on 323 children diagnosed with MPP and pulmonary consolidation at our hospital from September 2020 to October 2023. Patients were divided into BAL group (n = 163) and non-BAL group (n = 160). Clinical data, laboratory findings, and imaging features (including quantified pulmonary consolidation volume) were collected. Univariate and multivariate logistic regression analyses were employed to identify independent predictors for BAL intervention. A nomogram was constructed based on significant factors. The model's performance was assessed using the receiver operating characteristic (ROC) curve, concordance index (C-index), calibration plot, and internal validation via bootstrap resampling. Multivariate logistic regression identified lung atelectasis, older age, greater pulmonary consolidation volume (percentage of total lung volume), and longer hospital stay as independent risk factors for BAL. Corticosteroid treatment emerged as a protective factor. The nomogram developed from these variables yielded an area under the ROC curve (AUC) of 0.87 (95% CI: 0.83-0.91), with good calibration. Internal validation confirmed the robustness of the model. Lung atelectasis, pulmonary consolidation extent, length of hospitalization, age, and corticosteroid therapy are key determinants for BAL necessity in MPP children with consolidation. The proposed nomogram demonstrates strong discrimination, calibration, and clinical applicability, facilitating personalized evaluation of BAL indication.
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