Evidence map›Paper›PMID 41513626›Full record

ArticleBlood cancer journal2026

Genome-wide association study of event-free survival in follicular lymphoma patients treated with front-line immunochemotherapy.

Hervé Ghesquières, Youenn Drouet, Susan L Slager, Franck Morschhauser, Edith Julia, Sara Galimberti, Dennis Robinson, Melissa C Larson, Quentin Testard, Bruno Tesson and 15 more

Abstract read
In one paragraph

Article in Blood cancer journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Hervé GhesquièresDepartment of Hematology, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre Benite, France. herve.ghesquieres@chu-lyon.fr.ORCID 0000-0002-3131-3718
Youenn DrouetPrevention & Public Health Department, Centre Léon Bérard, Lyon, France.
Susan L SlagerQuantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-5173-4712
Franck MorschhauserDepartment of Hematology, CHU Lille, Univ. Lille, ULR 7365 - GRITA - Groupe de Recherche sur les formes Injectables et les Technologies Associées, Lille, France.
Edith JuliaDepartment of Hematology, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre Benite, France.ORCID 0000-0003-3325-8107
Sara GalimbertiDepartment of Clinical and Experimental Medicine, Hematology, University of Pisa, Pisa, Italy.
Dennis RobinsonQuantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
Melissa C LarsonQuantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
Quentin TestardNGS-HCL Platform, Bioinformatics Group, Hospices Civils de Lyon, Bron, France.
Bruno TessonDepartment of Bioinformatics, Lymphoma Study Association Clinical Research (LYSARC), Hopital Lyon Sud, Pierre Benite, France.
Jean-François DeleuzeCEA, Centre National de Recherche en Génomique Humaine (CNRGH), Université Paris-Saclay, Evry, France.
Anne BolandCEA, Centre National de Recherche en Génomique Humaine (CNRGH), Université Paris-Saclay, Evry, France.
Emilie ThomasBioinformatics Platform, Synergie Lyon Cancer Foundation, Lyon, France.
Christine LassetPrevention & Public Health Department, Centre Léon Bérard, Lyon, France.
Anne J NovakDivision of Hematology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-7904-1651
Luc XerriInstitut Paoli-Calmettes, CRCM and Aix-Marseille University, Marseille, France.
Stefano LuminariHematology Unit, Azienda USL IRCCS of Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0001-8446-2285
Aurelie VerneyCIRI, Centre International de Recherche en Infectiologie, Team Lymphoma Immuno-Biology, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.
Camille LaurentInstitut Universitaire Cancer-Oncopole, Centre de Recherches en Cancérologie de Toulouse, INSERM U1037, Toulouse, France.
Lisa M RimszaDivision of Hematopathology, Mayo Clinic, Scottsdale, AZ, USA.
Thomas M HabermannDivision of Hematology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0003-3532-9132
Massimo FedericoCHIMOMO Department, University of Modena and Reggio Emilia, Modena, Italy.
Brian K LinkDivision of Hematology, University of Iowa, Iowa City, IA, USA.
Gilles SallesLymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA.ORCID 0000-0002-9541-8666
James R CerhanQuantitative Health Sciences, Mayo Clinic, Rochester, MN, USA. cerhan.james@mayo.edu.ORCID 0000-0002-7482-178X

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
The Role of Monocytes in non-Hodgkin LymphomaP50CA097274 · NCI · UNIVERSITY OF IOWA · PI HOUTMAN, JON C.D. · 2002 to 2021
$45.7M
The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study (Supplement)U01CA195568 · NCI · MAYO CLINIC ROCHESTER · PI CERHAN, JAMES R, FLOWERS, CHRISTOPHER R · 2015 to 2025
$22.1M
NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA097274NCI NIH HHS U01 CA195568U.S. Department of Health & Human Services | National Institutes of Health (NIH) P50 CA97274, U01 CA195568
6 · The paper itself

Abstract

Genome-wide association studies (GWAS) have identified germline genetic variants for follicular lymphoma (FL) susceptibility. We conducted a GWAS of prognosis in FL patients to identify genetic predictors of event-free survival (EFS) as well as failure within the first 24 months after treatment initiation (EFS24) using patients treated with rituximab-based immunochemotherapy from three clinical trials and one prospective observational study (N = 1054). Statistical approaches consisted of a pooled GWAS of the four cohorts and a leave-one-cohort-out (LOCO) strategy to identify robust findings that replicated across the four cohorts. The top SNPs for EFS and EFS24 were marked by rs72625024 at 3q27.3 near FETUB and HRG (P = 9.37 × 10

Indexed as

Genome-Wide Association StudyImmunotherapyLymphoma, FollicularAgedAntineoplastic Combined Chemotherapy ProtocolsDisease-Free SurvivalFemaleHumansMaleMiddle AgedPolymorphism, Single NucleotidePrognosisRituximabRituximab

Identifiers

PMID41513626
PMCPMC12876897

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.