Evidence map›Paper›PMID 41513412›Full record

Trial reportBMJ open2026

Understanding psoriasis care costs and the impact of comorbidities: a time-driven activity-based costing analysis in an integrated practice unit.

Joke Borzée, Brecht Cardoen, Filip Roodhooft, Emma Vyvey, Jo Lambert

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05480917 (Value Based Healthcare in Psoriasis - IRIS Trial), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05480917 naunknown statusnot on this map

Value Based Healthcare in Psoriasis - IRIS Trial

TypeinterventionalSponsorUniversity Hospital, GhentRan2023 to 2025Enrolled350ConditionsPsoriasisArmsPatients receiving PsoPlus care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joke BorzéeVlerick Business School, Ghent, Belgium joke.borzee@hotmail.com.ORCID http://orcid.org/0000-0001-9827-1009
Brecht CardoenVlerick Business School, Ghent, Belgium.
Filip RoodhooftVlerick Business School, Ghent, Belgium.
Emma VyveyDepartment of Dermatology, University Hospital Ghent, Ghent, Flanders, Belgium.
Jo LambertDepartment of Dermatology, University Hospital Ghent, Ghent, Flanders, Belgium.ORCID http://orcid.org/0000-0001-5303-9310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe study aims to evaluate the cost of managing psoriasis and its comorbidities across multiple medical departments and to identify cost determinants based on patient, disease and treatment characteristics. Additionally, it compares the cost of care with reimbursements under the fee-for-service (FFS) system to assess how well they reflect patient-specific care needs.

designSeven-step, time-driven activity-based costing (TD-ABC) analysis based on direct observations and interviews to generate patient-level cost estimates over the full cycle of care for participants prospectively enrolled in a clinical trial.

settingAn integrated practice unit (IPU) at a Belgian University Hospital, centred around the treatment of psoriasis, including the management of associated comorbidities.

participantsA total of 52 patients meeting the trial's inclusion criteria, enrolled between January 2023 and November 2023, undergoing treatment within the IPU.

resultsThe individual cost of care over a 6-month period ranged from €169.78 to €1454.97, highlighting significant variability. Major cost drivers included mental health status and disease severity. Additionally, the presence of one or more comorbidities had a substantial impact on care costs, affecting not only expenses directly related to comorbidity management but often also those associated with dermatological care. Finally, a comparison between the TD-ABC cost variability and reimbursement tariffs variability revealed disparities, indicating that current tariffs do not sufficiently account for patient-specific cost differences.

conclusionsHealthcare delivery and costing studies often adopt a fragmented approach, limiting cost insights into the full cycle of care for a medical condition. The TD-ABC methodology can address this gap by generating detailed, patient-level cost estimates for both primary illness management and related comorbidities. Our findings underscore the importance of including comorbidity-related costs when discussing a condition's overall economic burden while also revealing significant cost variability among patients with the same disease. Notably, these variations are not sufficiently addressed by the current FFS reimbursement system. TRIAL REGISTRATION NUMBER: NCT05480917 (ClinicalTrials.gov).

Indexed as

Health Care CostsPsoriasisAdultAgedBelgiumComorbidityCosts and Cost AnalysisFee-for-Service PlansFemaleHumansMaleMiddle AgedProspective StudiesSeverity of Illness IndexChronic DiseaseHealth Care CostsHEALTH ECONOMICSMultimorbidityPatient-Centered CarePsoriasis

Identifiers

PMID41513412
PMCPMC12815197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.