Evidence map›Paper›PMID 41512653›Full record

ArticleDrug and alcohol dependence2026

Leveraging a digital health intervention to improve recovery outcomes among people with substance misuse experiencing housing insecurity.

Vidya Eswaran, Fanghong Dong, Xiao Li, Hannah S Szlyk, Nathaniel A Dell, Erin Kasson, Jessica Williams, Patricia A Cavazos-Rehg

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vidya EswaranDepartment of Emergency Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Box 8072, St. Louis, MO 63110, United States. Electronic address: vidya@wustl.edu.
Fanghong DongDepartment of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St. Louis, MO 63110, United States. Electronic address: dong.f@wustl.edu.
Xiao LiDepartment of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St. Louis, MO 63110, United States. Electronic address: lixiao@wustl.edu.
Hannah S SzlykDepartment of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St. Louis, MO 63110, United States. Electronic address: szlyk@wustl.edu.
Nathaniel A DellDepartment of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St. Louis, MO 63110, United States. Electronic address: delln@wustl.edu.
Erin KassonDepartment of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St. Louis, MO 63110, United States. Electronic address: erinmkasson@wustl.edu.
Jessica WilliamsDepartment of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St. Louis, MO 63110, United States. Electronic address: jcwilliams@wustl.edu.
Patricia A Cavazos-RehgDepartment of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St. Louis, MO 63110, United States. Electronic address: pcavazos@wustl.edu.

Funding

Transdisciplinary Training in Addictions ResearchT32DA015035 · NIDA · WASHINGTON UNIVERSITY · PI Leopoldo J Cabassa, Patricia A Cavazos-Rehg · 2002 to 2026
$5.3M
A digital intervention to decrease self-stigma among pregnant and postpartum women with opioid use disorderR44DA055161 · NIDA · RISSANA, LLC · PI Patricia A Cavazos-Rehg, Micah Goodman · 2022 to 2026
$2.0M
PRomoting Excellence through Pain and Addiction Research Enhancement (PREPARE)T90NR021683 · NINR · WASHINGTON UNIVERSITY · PI Burel R. Goodin · 2024 to 2026
$854k
mHealth to help pregnant and postpartum women in recovery for opioid use disorderR34DA050453 · NIDA · WASHINGTON UNIVERSITY · PI CAVAZOS-REHG, PATRICIA A · 2020 to 2022
$716k
NIDA NIH HHS R34 DA050453NIDA NIH HHS R44 DA055161NIDA NIH HHS T32 DA015035NINR NIH HHS T90 NR021683
6 · The paper itself

Abstract

backgroundPeople with substance use disorders (PwSUD) who experience housing insecurity have disproportionate overdose deaths. Digital interventions may improve care among PwSUD, but evidence specifically for housing-insecure PwSUD, who face unique barriers, remains limited.

methodsWe examined the efficacy of a mHealth tool (uMAT-R) among people who have misused substances and reported current housing insecurity. Substance use, cravings, access to basic needs, social disconnection, and digital literacy were assessed at baseline and 1 month and compared by uMAT-R use. Generalized estimating equations were employed to assess the efficacy of the intervention.

resultsParticipants who logged into uMAT-R were less likely to report other non-opioid illicit drug use (aOR (95 %CI): 0.49(0.29, 0.85)). Similarly, those who messaged the e-coach were less likely to report using opioids (aOR(95 %CI): 0.39(0.21, 0.73)) or other illicit drugs (aOR (95 % CI): 0.53(0.30, 0.92)) during past 30-days. Significant interaction effects were found in uMAT-R use by time in cravings (Coef (95 %CI): -2.11(-4.07, -0.17)) and perceived burdensomeness (Coef(95 %CI): -2.62 (-4.91, -0.36)). Messaging an e-coach by time was significantly associated with improved health literacy (Coef (95 %CI): 0.61(0.05, 1.18)) and decreased thwarted belongingness (Coef(95 %CI): -0.36 (-0.71, -0.02).

conclusionOur preliminary findings suggest that people who have misused substances and experience housing insecurity may benefit from uMAT-R, which was associated with improved recovery outcomes. Future research is needed to examine the unique barriers experienced by this population and how mHealth tools can be used to provide tailored, equitable access to supportive resources to reduce barriers and promote long-term recovery.

Indexed as

Housing InstabilitySubstance-Related DisordersAdultDigital HealthFemaleHumansMaleTelemedicineTreatment OutcomeDigital InterventionHousing insecurityMHealthSubstance Use

Identifiers

PMID41512653
PMCPMC12955705

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.