Evidence map›Paper›PMID 41512485›Full record

ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2026

Reduced neural speech tracking in adolescents with listening difficulty.

Katsuaki Kojima, Chunyan Liu, Shelley Ehrlich, Harvey Dillon, Chelsea Blankenship, Lina Motlagh Zadeh, Jennifer Vannest, Lisa Hunter, Srikantan Nagarajan, David R Moore

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Katsuaki KojimaPerinatal Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, United States; Department of Pediatrics, University of Cincinnati College of Medicine, 3230 Eden Avenue, Cincinnati, OH 45267, United States. Electronic address: katsuaki.kojima@cchmc.org.
Chunyan LiuDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, United States.
Shelley EhrlichDepartment of Pediatrics, University of Cincinnati College of Medicine, 3230 Eden Avenue, Cincinnati, OH 45267, United States; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, United States.
Harvey DillonDepartment of Linguistics, Macquarie University, Sydney, Australia; Manchester Center for Audiology and Deafness, School of Health Science, University of Manchester, Manchester, United Kingdom.
Chelsea BlankenshipDivision of Patient Services Research, Cincinnati Children's Hospital Medical Center, 240 Albert Sabin Way, Cincinnati, OH 45229, United States; Department of Communication Sciences and Disorders, University of Cincinnati, 3225 Eden Avenue, Cincinnati, OH 45267, United States.
Lina Motlagh ZadehDepartment of Communication Sciences and Disorders, University of Cincinnati, 3225 Eden Avenue, Cincinnati, OH 45267, United States.
Jennifer VannestDepartment of Communication Sciences and Disorders, University of Cincinnati, 3225 Eden Avenue, Cincinnati, OH 45267, United States.
Lisa HunterDivision of Patient Services Research, Cincinnati Children's Hospital Medical Center, 240 Albert Sabin Way, Cincinnati, OH 45229, United States; Department of Communication Sciences and Disorders, University of Cincinnati, 3225 Eden Avenue, Cincinnati, OH 45267, United States.
Srikantan NagarajanDepartments of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States.
David R MooreDepartment of Pediatrics, University of Cincinnati College of Medicine, 3230 Eden Avenue, Cincinnati, OH 45267, United States; Manchester Center for Audiology and Deafness, School of Health Science, University of Manchester, Manchester, United Kingdom; Division of Patient Services Research, Cincinnati Children's Hospital Medical Center, 240 Albert Sabin Way, Cincinnati, OH 45229, United States.

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Idiopathic auditory dysfunction in children: nature and mechanismsR01DC014078 · NIDCD · CINCINNATI CHILDRENS HOSP MED CTR · PI MOORE, DAVID · 2015 to 2019
$3.0M
Uncovering the Neural Mechanisms and Antecedent Factors of Listening Difficulty in Preterm ChildrenR21DC022030 · NIDCD · CINCINNATI CHILDRENS HOSP MED CTR · PI Katsuaki Kojima · 2024 to 2026
$602k
NCATS NIH HHS UL1 TR001425NIDCD NIH HHS R01 DC014078NIDCD NIH HHS R21 DC022030
6 · The paper itself

Abstract

objectiveTo investigate neural mechanisms underlying speech-in-speech listening in adolescents with listening difficulties (LiD).

methodsNeural speech tracking (NST) was assessed using magnetoencephalography (MEG; 275 sensors) in 21 adolescents with LiD (11 females), identified by caregiver report, and 25 typically developing (TD) peers (10 females), all with normal audiograms and frequency-matched on age, sex, race, and ethnicity. Participants completed a cocktail-party task with target speech alone and with competing streams that varied in talker and spatial cues. NST was quantified using theta-band (4-8 Hz) inter-event phase coherence (IEPC) to acoustic edges.

resultsAdolescents with LiD showed reduced target-speech NST relative to TD peers, with comparable competitor tracking. Theta-band IEPC correlated with listening ability (partial R

conclusionsLiD is characterized by impaired processing of attended speech rather than enhanced competitor processing or generalized auditory disengagement. Reduced integration of talker and spatial cues in LiD may contribute to real-world listening challenges. SIGNIFICANCE: Theta‑band NST provides a clinically relevant neural index of everyday listening and may guide interventions targeting selective attention and cue integration.

Indexed as

SpeechSpeech PerceptionAcoustic StimulationAdolescentChildFemaleHumansMagnetoencephalographyMaleAuditory processing disorderCocktail partyHearing lossListening difficultyMagnetoencephalographySpeech-in-noiseSpeech tracking

Identifiers

PMID41512485
PMCPMC13042267

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.