Evidence map›Paper›PMID 41512066›Full record

ArticleScience advances2026

Whole-brain meso-vein imaging in living humans using fast 7-T MRI.

Omer Faruk Gulban, Rüdiger Stirnberg, Desmond Ho Yan Tse, Alessandra Pizzuti, Kenshu Koiso, Mario Eduardo Archila-Melendez, Laurentius Renzo Huber, Saskia Bollmann, Rainer Goebel, Kendrick Kay and 1 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Endothelial Continuum and Capillary Specialization in Pulmonary Vascular Development.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  2. Mesoscale Whole-Brain TMagnetic resonance in medicine · 2026
    Article
  3. Article
  4. An MRI Atlas of Regional Brain Vulnerability to Metastatic Disease.medRxiv : the preprint server for health sciences · 2026
    Article
  5. Article
  6. Motion- and Field-Robust Mesoscopic Whole-BrainMagnetic resonance in medicine · 2026
    Article
  7. Article
  8. bioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Omer Faruk GulbanDepartment of Cognitive Neuroscience(CN), FPN, Maastricht University, Maastricht, Netherlands.ORCID 0000-0001-7761-3727
Rüdiger StirnbergGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.ORCID 0000-0001-7021-1063
Desmond Ho Yan TseMax Planck Institute for Empirical Aesthetics, Frankfurt, Germany.ORCID 0000-0003-2559-7707
Alessandra PizzutiDepartment of Cognitive Neuroscience(CN), FPN, Maastricht University, Maastricht, Netherlands.ORCID 0000-0002-3311-9118
Kenshu KoisoDepartment of Cognitive Neuroscience(CN), FPN, Maastricht University, Maastricht, Netherlands.ORCID 0000-0001-5931-6294
Mario Eduardo Archila-MelendezDepartment of Biological Psychology and Cognitive Neurosciences (BPCN), Institute of Psychology, Friedrich-Schiller-Universitat, Jena, Germany.ORCID 0000-0002-2994-3067
Laurentius Renzo HuberAthinoula A. Martinos Center for Biomedical Imaging, MGH, MGB, Charlestown, USA.ORCID 0000-0002-3291-2202
Saskia BollmannSchool of Electrical Engineering and Computer Science (EECS), The University of Queensland, Brisbane, Australia.ORCID 0000-0001-8242-8008
Rainer GoebelDepartment of Cognitive Neuroscience(CN), FPN, Maastricht University, Maastricht, Netherlands.ORCID 0000-0003-1780-2467
Kendrick KayCenter for Magnetic Resonance Imaging (CMRR), Department of Radiology, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0001-6604-9155
Dimo IvanovDepartment of Cognitive Neuroscience(CN), FPN, Maastricht University, Maastricht, Netherlands.ORCID 0000-0001-9387-5823

Funding

Deep sampling of cognitive effects in the human visual systemR01EY034118 · NEI · UNIVERSITY OF MINNESOTA · PI CLAYTON E CURTIS, Kendrick Norris Kay · 2023 to 2026
$1.9M
NEI NIH HHS R01 EY034118
6 · The paper itself

Abstract

Noninvasive measurement of the human brain's angioarchitecture is essential for understanding functional neuroimaging signals, diagnosing cerebrovascular diseases, and tracking neurodegeneration. Ultrahigh-field MRI now enables mesoscopic (<0.5 millimeters) imaging, revealing vascular details previously inaccessible in vivo. Yet current approaches face two barriers: Scan times often exceed 40 minutes, and the conventional visualization methods remain limited for navigating the vasculature. Here, we present a fast whole-brain MRI protocol that resolves the venous network at 0.35 millimeters in under 7 minutes. We also introduce processing and visualization techniques that distinguish vessel types and more intuitively navigate the vasculature. These advances allow in vivo reproduction of the seminal vasculature images of Henri M. Duvernoy and provide whole-brain intracortical meso-vein maps in humans. Our methods lay the groundwork for detailed examination of vascular organization across individuals, brain regions, and cortical layers. More generally, these methods make mesoscopic imaging of angioarchitecture viable for broad neuroscientific and clinical applications.

Indexed as

BrainCerebral VeinsMagnetic Resonance ImagingVeinsBrain MappingHumansImage Processing, Computer-AssistedMale

Identifiers

PMID41512066
PMCPMC12787541

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.