Evidence map›Paper›PMID 41512029›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

A self-wrapping, bioresorbable neural interface for wireless multimodal therapy of localized peripheral nerve injury.

Pengchuan Liu, Lianjie Zhou, Dian Xu, Dongqi An, Yifei Lu, Bofan Hu, Yuting Shao, Ningge Huang, Chengjie Guo, Li Chen and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Pengchuan Liu *Institute of Optoelectronics and College of Future Information Technology, College of Intelligent Robotics and Advanced Manufacturing, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai 200438, China.ORCID 0009-0007-0009-2186
Lianjie Zhou *Institute of Optoelectronics and College of Future Information Technology, College of Intelligent Robotics and Advanced Manufacturing, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai 200438, China.ORCID 0000-0002-9285-2176
Dian Xu *School of Mechanics and Aerospace Engineering, State Key Laboratory of Structural Analysis, Optimization and Computer Aided Engineering Software for Industrial Equipment, and International Research Center for Computational Mechanics, Dalian University of Technology, Dalian, Liaoning 116024, China.ORCID 0000-0001-9373-924X
Dongqi AnSchool of Mechanics and Aerospace Engineering, State Key Laboratory of Structural Analysis, Optimization and Computer Aided Engineering Software for Industrial Equipment, and International Research Center for Computational Mechanics, Dalian University of Technology, Dalian, Liaoning 116024, China.
Yifei LuInstitute of Optoelectronics and College of Future Information Technology, College of Intelligent Robotics and Advanced Manufacturing, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai 200438, China.
Bofan HuInstitute of Optoelectronics and College of Future Information Technology, College of Intelligent Robotics and Advanced Manufacturing, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai 200438, China.
Yuting ShaoDepartment of Ophthalmology, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, China.
Ningge HuangInstitute of Optoelectronics and College of Future Information Technology, College of Intelligent Robotics and Advanced Manufacturing, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai 200438, China.
Chengjie GuoSchool of Mechanics and Aerospace Engineering, State Key Laboratory of Structural Analysis, Optimization and Computer Aided Engineering Software for Industrial Equipment, and International Research Center for Computational Mechanics, Dalian University of Technology, Dalian, Liaoning 116024, China.ORCID 0009-0008-9397-255X
Li ChenInternational Institute for Intelligent Nanorobots and Nanosystems & State Key Laboratory of Surface Physics, Fudan University, Shanghai 200438, China.
Jinbao LiSchool of Mechanics and Aerospace Engineering, State Key Laboratory of Structural Analysis, Optimization and Computer Aided Engineering Software for Industrial Equipment, and International Research Center for Computational Mechanics, Dalian University of Technology, Dalian, Liaoning 116024, China.ORCID 0009-0000-7031-4636
Jiahao LiInstitute of Optoelectronics and College of Future Information Technology, College of Intelligent Robotics and Advanced Manufacturing, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai 200438, China.ORCID 0009-0003-6574-7455
Fuying LiangInstitute of Optoelectronics and College of Future Information Technology, College of Intelligent Robotics and Advanced Manufacturing, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai 200438, China.
Junhan LiuInstitute of Optoelectronics and College of Future Information Technology, College of Intelligent Robotics and Advanced Manufacturing, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai 200438, China.ORCID 0009-0007-3022-2738
Gaoshan HuangInstitute of Optoelectronics and College of Future Information Technology, College of Intelligent Robotics and Advanced Manufacturing, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai 200438, China.ORCID 0000-0002-0525-7177
Yongfeng MeiInstitute of Optoelectronics and College of Future Information Technology, College of Intelligent Robotics and Advanced Manufacturing, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai 200438, China.ORCID 0000-0002-3314-6108
Rui LiSchool of Mechanics and Aerospace Engineering, State Key Laboratory of Structural Analysis, Optimization and Computer Aided Engineering Software for Industrial Equipment, and International Research Center for Computational Mechanics, Dalian University of Technology, Dalian, Liaoning 116024, China.
Enming SongInstitute of Optoelectronics and College of Future Information Technology, College of Intelligent Robotics and Advanced Manufacturing, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai 200438, China.ORCID 0000-0002-2658-904X

Funding

Ministry of Science and Technology of the People's Republic of China (MOST) 2022ZD0209900MOST | National Natural Science Foundation of China (NSFC) 62204057 62304044Science and Technology Commission of Shanghai Municipality (STCSM) 22ZR1406400
6 · The paper itself

Abstract

High-precision in vivo therapeutic technologies that establish three-dimensional (3D), multimodal neural interfaces with targeted biotissues offer significant clinical potential for the timely treatments of localized peripheral nerve injury (PNI). Current approaches for this purpose such as implantable devices face challenges in terms of percutaneous wires and/or nondegradable designs, and support only single-mode operation that lack microscale spatial resolution. Here, we develop a miniaturized, self-wrapping system that yields wireless, multimodal neural interfaces with 3D adaptation across localized peripheral nerves at scales ranging from tens of micrometers (15 μm) to millimeters. Such platform integrates multilayer architectures that include SiN

Indexed as

Absorbable ImplantsPeripheral Nerve InjuriesWireless TechnologyAnimalsCombined Modality TherapyDrug Delivery SystemsPeripheral NervesPhotothermal TherapyRatsbioresorbable electronicsdrug deliveryperipheral nerve repairphotothermal therapyself-wrapping bistable neural interface

Identifiers

PMID41512029
PMCPMC12799165

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.