Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
24 authors.
Seiga KomiyamaDivision of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.ORCID 0009-0007-6175-0007
Yotaro KodairaDivision of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.
Rae MaedaMulti-Omics Platform, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.
Yuki SugiuraHuman Biology-Microbiome-Quantum Research Center (WPI-Bio2Q), Keio University, Tokyo 108-8345, Japan.ORCID 0000-0002-6983-8958
Koichiro SuzukiDivision of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.ORCID 0009-0006-3853-9628
Aiko SaekiDivision of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.ORCID 0000-0002-5120-6020
Yusuke KinashiDivision of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.
Hiroyuki OguchiDivision of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.ORCID 0009-0004-8597-7378
Kokona TakanoDivision of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.ORCID 0009-0006-5158-1628
Satoshi OnawaGut Environmental Design Group, Kanagawa Institute of Industrial Science and Technology, Kawasaki 210-0821, Japan.
Ako MatsuiDivision of Allergy and Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka 811-1347, Japan.ORCID 0000-0003-3457-7433
Eita SasakiDivision of Analytical Chemistry for Drug Discovery, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.
Kisara Hattori-MuroiDivision of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.
Shunsuke KimuraDivision of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.ORCID 0000-0001-9408-2884
Yumiko FujimuraDivision of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.ORCID 0009-0004-0370-4262
Yuyo KaHumanized Model Laboratory, Animal Resource Technical Research Center, Central Institute for Experimental Medicine and Life Science, Kanagawa 210-0821, Japan.ORCID 0000-0002-9367-7162
Tomoyuki OguraHumanized Model Laboratory, Animal Resource Technical Research Center, Central Institute for Experimental Medicine and Life Science, Kanagawa 210-0821, Japan.ORCID 0009-0002-2482-1076
Kenjiro HanaokaDivision of Analytical Chemistry for Drug Discovery, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.ORCID 0000-0003-0797-4038
Minako ItoDivision of Allergy and Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka 811-1347, Japan.
Hiroshi WataraiDepartment of Immunology and Stem Cell Biology, Kanazawa University, Kanazawa 920-8640, Japan.
Tsuneyasu KaishoDepartment of Immunology, Institute of Advanced Medicine, Wakayama Medical University, Wakayama 641-8509, Japan.ORCID 0000-0003-2616-1665
Nobuyuki UdagawaDepartment of Biochemistry, Matsumoto Dental University, Shiojiri 399-0781, Japan.
Daisuke Takahashi *Division of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.ORCID 0000-0001-8624-1160
Koji Hase *Division of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105-8512, Japan.ORCID 0000-0001-9550-2334
Interleukin-17-producing γδT cells (γδT17 cells) play a dual role in immune regulation, serving as both protectors in various tissues and orchestrators of inflammatory responses in autoimmune diseases, including experimental autoimmune encephalomyelitis (EAE), a rodent model of multiple sclerosis. However, the ontology and repertoires of encephalitogenic γδT17 cells remain unclear. In this study, we demonstrate that the encephalitogenicity of γδT17 cells is conferred through microfold cell (M cell)-dependent uptake of commensal bacteria in Peyer's patches. Specifically, CXCR6
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
M cell-dependent commensal uptake confers encephalitogenic phenotypes on γδT17 cells in Peyer's patches. · full record | OpenQuestion