Evidence map›Paper›PMID 41511991›Full record

ArticleJournal of the American Chemical Society2026

Accelerated and Green Synthesis of

Jyotirmoy Ghosh, Nicolás M Morato, William A LeFever, R Graham Cooks

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Accelerated Chemistry in Microdroplets.Accounts of chemical research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jyotirmoy GhoshDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.ORCID 0000-0002-3592-4903
Nicolás M MoratoPurdue Institute for Cancer Research, Purdue University, 201 S. University Street, West Lafayette, Indiana 47907, United States.ORCID 0000-0003-0218-407X
William A LeFeverDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.
R Graham CooksDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.ORCID 0000-0002-9581-9603

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI ANDREW D MESECAR · 1985 to 2026
$43.4M
High throughput infrastructure for reaction screening and bioassaysUH3TR004139 · NCATS · PURDUE UNIVERSITY · PI Robert Graham Cooks · 2024 to 2026
$4.1M
High throughput infrastructure for reaction screening and bioassaysUG3TR004139 · NCATS · PURDUE UNIVERSITY · PI COOKS, ROBERT GRAHAM · 2022 to 2023
$1.8M
NCATS NIH HHS UG3 TR004139NCATS NIH HHS UH3 TR004139NCI NIH HHS P30 CA023168
6 · The paper itself

Abstract

Nitrogen-based heterocycles are widespread in pharmaceutical and agricultural products, yet methods to synthesize them are often inefficient, requiring long reaction times, high temperatures, and catalysts. Here, we report an accelerated, simple, and generalized green synthetic method for the conversion of a series of amines into diverse

Identifiers

PMID41511991
PMCPMC12856915

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.