Observational studyPloS one2026
Comparison of four diagnostic indices for metabolic syndrome in a Northern Spanish population.
Observational study in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Comparative Effects of SGLT2 Inhibitors and GLP-1 Receptor Agonists on Composite Surrogate Markers of Insulin Resistance: A Real-World Study Using METS-IR and SPISE.Journal of clinical medicine · 2026Article
- Correction: Comparison of four diagnostic indices for metabolic syndrome in a Northern Spanish population.PloS one · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiometabolic diseases are the leading cause of death worldwide, and early identification of individuals at risk is essential to reduce their burden. This study compared the performance of four diagnostic indices - the Visceral Adiposity Index (VAI), Body Mass Index (BMI), Waist Circumference (WC), and Atherogenic Index (AI) - in predicting Metabolic Syndrome (MetS) in a primary care population from northern Spain. A retrospective observational study was conducted using data from the CRONAP cohort (n = 3,107). Anthropometric and analytical parameters were analyzed using logistic regression and ROC curves. The VAI showed the highest predictive capacity for MetS (AUC = 0.779), followed by WC (0.756), BMI (0.730), and AI (0.665). In the MetS group, higher and statistically significant values were observed for glucose, glycated hemoglobin, triglycerides, blood pressure, BMI, and WC (p < 0.001), while HDL-cholesterol and glomerular filtration rate were lower. VAI outperformed the other indices in identifying MetS and may serve as a useful screening tool in primary care settings; however, as this is a retrospective, single-region study, further research is required to validate its diagnostic cut-off and generalizability to other populations.
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