Evidence map›Paper›PMID 41511877›Full record

ArticleCell reports2026

Genetic identification of mouse trigeminal afferents responsible for mechanical allodynia.

Tingting Li, Hyeonwi Son, Vipin Arora, John Shannonhouse, Sinu Kumari, Dennis Chang, Michael Caterina, Yu Shin Kim, Man-Kyo Chung

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tingting LiDepartment of Neural and Pain Sciences, School of Dentistry, Center to Advance Chronic Pain Research, University of Maryland Baltimore, Baltimore, MD 21201, USA.
Hyeonwi SonDepartment of Endodontics, School of Dentistry, University of Alabama at Birmingham, Birmingham, AL 35233, USA; Ilsong Institute of Life Science, Hallym University, Seoul, Republic of Korea; Department of Biomedical Gerontology, Graduate School of Hallym University, Chuncheon, Republic of Korea.
Vipin AroraDepartment of Neural and Pain Sciences, School of Dentistry, Center to Advance Chronic Pain Research, University of Maryland Baltimore, Baltimore, MD 21201, USA.
John ShannonhouseDepartment of Endodontics, School of Dentistry, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Sinu KumariDepartment of Neural and Pain Sciences, School of Dentistry, Center to Advance Chronic Pain Research, University of Maryland Baltimore, Baltimore, MD 21201, USA.
Dennis ChangDepartment of Neurosurgery, Neurosurgery Pain Research Institute, Johns Hopkins School of Medicine, Baltimore, MD 212053, USA.
Michael CaterinaDepartment of Neurosurgery, Neurosurgery Pain Research Institute, Johns Hopkins School of Medicine, Baltimore, MD 212053, USA; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA; Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
Yu Shin KimDepartment of Endodontics, School of Dentistry, University of Alabama at Birmingham, Birmingham, AL 35233, USA. Electronic address: ykim28@uab.edu.
Man-Kyo ChungDepartment of Neural and Pain Sciences, School of Dentistry, Center to Advance Chronic Pain Research, University of Maryland Baltimore, Baltimore, MD 21201, USA. Electronic address: mchung@umaryland.edu.

Funding

Trigeminal nociceptors: Neural intersection of chronic pain and alveolar bone remodelingR35DE030045 · NIDCR · UNIVERSITY OF MARYLAND BALTIMORE · PI Man-Kyo Chung · 2020 to 2026
$7.1M
Functional peripheral and central vagal neural circuits of interoception inhibiting painR01DE031477 · NIDCR · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Man-Kyo Chung, Yu Shin Kim · 2022 to 2026
$3.9M
Interdisciplinary Training in Biobehavioral Pain ResearchT32NS070201 · NINDS · JOHNS HOPKINS UNIVERSITY · PI DONG, XINZHONG, SMITH, MICHAEL T · 2010 to 2024
$3.6M
Chronic Intermittent Hypoxia and Hyperalgesic Priming - Administrative SupplementR01NS128574 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI NATHANIEL Aaron JESKE, Yu Shin Kim · 2023 to 2026
$2.4M
NIDCR NIH HHS R01 DE031477NIDCR NIH HHS R35 DE030045NINDS NIH HHS R01 NS128574NINDS NIH HHS T32 NS070201
6 · The paper itself

Abstract

The identities of primary afferents transducing mechanical allodynia following nerve injury remain unclear. We genetically label brushing-activated (BA) trigeminal ganglia (TG) neurons using Fos

Indexed as

HyperalgesiaNeurons, AfferentTrigeminal GanglionAnimalsIon ChannelsMaleMiceTrigeminal Nerve InjuriesIon ChannelsPiezo2 protein, mouseallodyniachronic painCP: Neurosciencemicenerve injurynociceptorsPiezo2trigeminal ganglia

Identifiers

PMID41511877
PMCPMC12951200

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.