Evidence map›Paper›PMID 41511670›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2026

Estimating the minimal important change of single-item measures using the adjusted predictive modeling method or the longitudinal confirmatory factor analysis method.

Berend Terluin, Yong Hao Pua, Piper Fromy, Andrew Trigg, Babette van der Zwaard, Jakob B Bjorner

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Berend TerluinDepartment of General Practice, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, 1081 HV, The Netherlands. b.terluin@amsterdamumc.nl.ORCID http://orcid.org/0000-0002-8944-5238
Yong Hao PuaDepartment of Physiotherapy, Singapore General Hospital, Singapore, Singapore.
Piper FromySeeingTheta, 2 Chemin des Vaux, 49400, Saumur, France.
Andrew TriggClinical Statistics and Analytics, Bayer plc, Reading, UK.
Babette van der ZwaardDepartment of Orthopedic Surgery, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.
Jakob B BjornerQualityMetric and IQVIA Company, Johnston, RI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecently developed minimal important change (MIC) estimation methods recover the mean individual MIC in a sample. These methods are the adjusted predictive modeling (APM) method and the longitudinal confirmatory factor analysis (LCFA) method. Both methods require LCFA of patient-reported outcome measure (PROM) data. In the APM-method, LCFA is used to estimate the reliability of the transition ratings, whereas in the LCFA-method, LCFA is used to estimate the latent MIC. However, LCFA cannot be performed if the PROM is a single item measure (SIM). Adding an auxiliary variable, that is correlated with the PROM, to the LCFA-model may be a solution. We developed three different LCFA-models in which an auxiliary variable is included. In this simulation study, we assessed the performance of the APM- and LCFA-methods to recover the true MIC of an SIM. We applied both methods to a real dataset in which the SIM was a numeric rating scale for pain.

methodsWe simulated 15,552 samples, varying in 11 parameters, and estimated the APM-based and LCFA-based MICs.

resultsThe APM-method performed well, except if the proportion improved was high or low, and the present state bias (PSB) was high. The LCFA-method performed well, irrespective of the proportion improved and the PSB. In the real data, the LCFA-based MIC was 17 (on a 100-point scale), whereas the estimated APM-based MIC was 4 points higher, probably due to a high proportion improved and a high PSB.

conclusionThe MIC of an SIM can be accurately estimated using an auxiliary PROM.

Indexed as

Models, StatisticalPatient Reported Outcome MeasuresComputer SimulationFactor Analysis, StatisticalHumansLongitudinal StudiesPsychometricsReproducibility of ResultsAdjusted predictive modeling methodLongitudinal confirmatory factor analysis methodMeaningful change thresholdMinimal important changePatient-reported outcome measureSingle item measureTransition ratings

Identifiers

PMID41511670
PMCPMC12789162

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.