Evidence map›Paper›PMID 41511576›Full record

ArticleLangenbeck's archives of surgery2026

Routine jejunostomy feeding after esophagectomy reduces early weight loss: a cohort study.

Jessica Yan-Seen Ng, Catherine Jenn Yi Cheang, Alexander W Phillips

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Article in Langenbeck's archives of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Jessica Yan-Seen NgThe Northern Oesophago-Gastric Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK. Jessica.Ng@health.qld.gov.au.ORCID http://orcid.org/0000-0002-9538-4435
Catherine Jenn Yi CheangThe Northern Oesophago-Gastric Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK.ORCID http://orcid.org/0000-0003-1824-3804
Alexander W PhillipsThe Northern Oesophago-Gastric Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK. alexander.phillips4@nhs.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeJejunostomy feeding tubes are commonly used during esophagectomy to provide postoperative nutritional support, but their impact on clinical outcomes remains uncertain.

methodsThis retrospective study included 507 patients who underwent esophagectomy for esophageal cancer at the Northern Oesophagogastric Unit between 2012 and 2014 and 2016-2019. Routine postoperative jejunostomy feeding was introduced in 2015. Outcomes measured were percentage weight change at 2, 6, 12, and 24 weeks postoperatively, length of hospital stay, weight loss in patients with major complications (Clavien-Dindo > 3), and long-term survival.

resultsOf the 507 patients, 290 received routine jejunostomy feeding and 217 did not. Jejunostomy-fed patients experienced significantly less weight loss at all measured time points, with weight loss at 2 weeks of 3.22% versus 7.24% (p < 0.001), at 6 weeks of 3.28% versus 8.30% (p < 0.001), at 3 months of 5.49% versus 10.38% (p < 0.001), and at 6 months of 6.89% versus 11.46% (p = 0.006). The greatest benefit was observed in patients receiving neoadjuvant chemotherapy followed by surgery, with the most pronounced difference at 3 months (5.23% vs. 11.63%). Median hospital stay was shorter in the jejunostomy group (11 versus 15 days), and long-term survival tended to be higher among jejunostomy-fed patients, although this did not reach statistical significance, although there was no significant difference in weight loss among patients with major complications.

conclusionRoutine postoperative jejunostomy feeding significantly reduces early postoperative weight loss after esophagectomy, particularly in patients receiving neoadjuvant chemotherapy. These benefits diminish by six months. Jejunostomy feeding may also shorten hospital stay and could be associated with improved long-term survival.

Indexed as

Enteral NutritionEsophageal NeoplasmsEsophagectomyJejunostomyPostoperative CareWeight LossAgedFemaleHumansLength of StayMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeEnteral nutritionEsophageal cancerEsophagectomyJejunostomyNutrition

Identifiers

PMID41511576
PMCPMC12827385

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