Evidence map›Paper›PMID 41511346›Full record

ArticleCells2025

Dissecting the Biological Functions of Various Isoforms of Ferredoxin Reductase for Cell Survival and DNA Damage Response.

Ken-Ichi Nakajima, Shakur Mohibi, Kyle Hong, Xinbin Chen, Jin Zhang

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ken-Ichi NakajimaComparative Oncology Laboratory, Schools of Veterinary Medicine and Medicine, University of California, Davis, CA 95616, USA.
Shakur MohibiComparative Oncology Laboratory, Schools of Veterinary Medicine and Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0001-5539-0841
Kyle HongComparative Oncology Laboratory, Schools of Veterinary Medicine and Medicine, University of California, Davis, CA 95616, USA.ORCID 0009-0008-6008-9656
Xinbin ChenComparative Oncology Laboratory, Schools of Veterinary Medicine and Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0002-4582-6506
Jin ZhangComparative Oncology Laboratory, Schools of Veterinary Medicine and Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0002-6835-920X

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI KC KENT LLOYD · 2002 to 2026
$84.9M
The nuclear Ferredoxin reductase and its role in tumor suppressionR01CA283368 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Xinbin Chen · 2024 to 2026
$1.4M
NCI NIH HHS P30 CA093373NCI NIH HHS R01 CA283368NIH HHS 1R01CA093373-00NIH HHS 1R01CA283368-02
6 · The paper itself

Abstract

The ferredoxin reductase

Indexed as

DNA DamageCell SurvivalHumansIsoenzymesMCF-7 CellsMitochondriaPromoter Regions, GeneticProtein IsoformsTumor Suppressor Protein p53IsoenzymesProtein IsoformsTumor Suppressor Protein p53DNA damage responseFDXR isoformsferredoxin reductasemitochondriap53

Identifiers

PMID41511346
PMCPMC12785329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.