Evidence map›Paper›PMID 41511081›Full record

ArticleJournal of virology2026

Variable and conserved features of copy-back viral genome populations generated

Yanling Yang, Yuchen Wang, Carolina B López

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yanling YangDepartment of Molecular Microbiology and Center for Women Infectious Disease Research, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0002-4808-515X
Yuchen WangDepartment of Molecular Microbiology and Center for Women Infectious Disease Research, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0009-0008-1056-1211
Carolina B LópezDepartment of Molecular Microbiology and Center for Women Infectious Disease Research, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0002-7669-6572

Funding

Defective Viral genomes in RSV pathogenesisR01AI137062 · NIAID · WASHINGTON UNIVERSITY · PI Carolina B. Lopez · 2018 to 2026
$4.2M
Long-term impact of persistent parainfluenza virus infectionR01AI188900 · NIAID · WASHINGTON UNIVERSITY · PI Carolina B. Lopez · 2025 to 2026
$1.2M
BJC Investigator ProgramNational Institute of Allergy and Infectious Diseases A137062National Institute of Allergy and Infectious Diseases AI188900NIAID NIH HHS R01 AI137062NIAID NIH HHS R01 AI188900
6 · The paper itself

Abstract

Copy-back viral genomes (cbVGs) are generated during the replication of negative-sense RNA viruses when the polymerase drops off from the genome and reattaches to the nascent strand. cbVGs have strong immunostimulatory properties and impact infection outcomes. Despite their importance, the composition and mechanisms of

Indexed as

Genome, ViralSendai virusAnimalsCell LineRNA ReplicationRNA, ViralVirus ReplicationRNA, Viralcopy-back viral genomenegative-sense RNA virusesSendai virusvariants

Identifiers

PMID41511081
PMCPMC12911868

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.