Evidence map›Paper›PMID 41511004›Full record

Trial reportDeutsches Arzteblatt international2026

The Treatment of Vertigo With a Digital Health App: Findings of the Prospective Randomized Controlled GEVE-I Trial.

Markus Wirth, Jannik Pieper, Ulrike Heller, Michael Bulitta, Daniel Schmitz, Barbara Wollenberg, Anne Ruck, Hubert Löwenheim, Walter Lehmacher, Stephan Wolpert

Abstract readRandomized Controlled TrialEquivalence Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Deutsches Arzteblatt international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Markus WirthDepartment of Otorhinolaryngology, Phoniatrics, and Pediatric Audiology, RWTH Aachen
Jannik PieperChair of Business and Social Policy, Otto Beisheim School of Management, Koblenz-Vallendar
Ulrike HellerOtorhinolaryngology Practice, Tübingen
Michael BulittaCRM Biometrics GmbH, Bornheim
Daniel SchmitzCRM Biometrics GmbH, Bornheim
Barbara WollenbergInstitute for Medical Statistics and Bioinformatics, University of Cologne
Anne RuckInstitute for Medical Statistics and Bioinformatics, University of Cologne
Hubert LöwenheimDepartment of Otorhinolaryngology, Technical University of Munich
Walter LehmacherDepartment of Otorhinolaryngology, University of Tübingen
Stephan WolpertDepartment of Otorhinolaryngology, Technical University of Munich

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVestibular vertigo is common and frequently leads to inability to work. We studied the clinical efficacy and safety of a digital health app (VH90D) for the treatment of vestibular vertigo.

methodsWe conducted a confirmatory, prospective, single-blinded, randomized, group-controlled, single-center, two-arm superiority trial with 212 participants. 106 of them (the intervention group) were treated with the app, and the other 106 (the control group) received treatment as usual with standard physiotherapy. The primary endpoint was the vertigo symptom score (VSS-sf-VER) at 12 weeks. The trial was entered into the German Clinical Trials Register (DRKS00024188).

resultsThe intergroup difference in the mean change of VSS-sf-VER score from baseline to week 12 was -7.9 points (95% confidence interval: [-9.5; -6.2]; Cohen's d: 1.55). The vertigo intensity score fell by an average of 12.7 points (clinically important difference [CID] -5 points; [-14.1; -11.2]) in the intervention group and 2.7 points (CID -5 points; [-3.7; -1.7]) in the control group (physiotherapy).

conclusionThe digital health app VH90D markedly reduced vertigo, with greater efficacy than the median value of six 20-minute physiotherapy sessions.

Indexed as

Mobile ApplicationsVertigoAdultAgedDigital HealthFemaleGermanyHumansMaleMiddle AgedPhysical Therapy ModalitiesProspective StudiesSingle-Blind MethodTreatment Outcome

Identifiers

PMID41511004
PMCPMC13196712

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.