ArticleExperimental physiology2026
Effects of high-intensity interval training on cardiac function in hypertensive and normotensive men: Effects of antihypertensive treatment.
Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Effects of high-intensity interval training on cardiac function in hypertensive and normotensive men: Effects of antihypertensive treatment.Experimental physiology · 2026Article
- Experimental Physiology Special Issue: Exercise as Medicine.Experimental physiology · 2026Article
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Authors and funding
9 authors.
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Abstract
Exercise training is recommended for individuals with hypertension because it has been shown to lower blood pressure and reverse left ventricular concentric remodelling and mass. However, it is unclear how hypertensive individuals respond in comparison to normotensive individuals and to what extent medical treatment affects the outcome of training. Our aim was to assess the effect of a 6 week high-intensity interval training (HIIT) intervention on cardiac adaptations in subjects with treated or untreated essential hypertension compared with normotensive control subjects. Cardiac function was evaluated by echocardiography in 11 medicated hypertensive men, who adhered to treatment during the intervention but refrained from medication for 4 days prior to and during measurements (MED-HYP), in 9 untreated hypertensive men (HYP) and in 10 age-matched normotensive men before and after HIIT. At baseline, HYP and MED-HYP had lower mitral valve E/A ratio (MED-HYP, 0.86 ± 0.2; HYP, 0.99 ± 0.1; P < 0.05) compared with normotensive men (1.37 ± 0.4). The HIIT stroke volume in normotensive men only improved maximum oxygen uptake (change, 178 ± 239 mL O
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