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ArticleKidney medicine2026

Kidney Replacement Therapy Sequences: Racial/Ethnic Disparities in End-Stage Kidney Disease Patients' 10-Year Treatment Histories.

Léa Pessin, Mary K Roberts, Avrum Gillespie, Catherine R Butler, Andrea Corradi, Arinala Randrianasolo, Jonathan Daw

Abstract read
In one paragraph

Article in Kidney medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Léa PessinDepartment of Political and Social Sciences, European University Institute, Fiesole, Italy.
Mary K RobertsLeverhulme Centre for Demographic Science Nuffield Department of Population HealthUniversity of Oxford42-43 Park End Street Oxford, UK OX1 1JD.
Avrum GillespieDivision of Nephrology, Hypertension, and Kidney Transplantation, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
Catherine R ButlerDivision of Nephrology, Department of Medicine and the Kidney Research Institute University of Washington, Seattle, WA.
Andrea CorradiDepartment of Criminal Justice and Criminology, Georgia Southern University, GA.
Arinala RandrianasoloLeverhulme Centre for Demographic Science Nuffield Department of Population HealthUniversity of Oxford42-43 Park End Street Oxford, UK OX1 1JD.
Jonathan DawLeverhulme Centre for Demographic Science Nuffield Department of Population HealthUniversity of Oxford42-43 Park End Street Oxford, UK OX1 1JD.

Funding

Strengthening Shared Decision-Making for Older Adults with Kidney Failure Considering Kidney TransplantK23DK129777 · NIDDK · UNIVERSITY OF WASHINGTON · PI Catherine R Butler · 2022 to 2026
$930k
NIDDK NIH HHS K23 DK129777
6 · The paper itself

Abstract

Rationale & Objective: There are substantial racial/ethnic disparities in access to kidney replacement therapies (KRT). Although existing work often focuses on discrete treatment outcomes, a holistic depiction of racial/ethnic groups' differential experiences requires a longitudinal approach. Study Design: A sequence analysis in national registry data. Setting & Participants: Adults aged 18-64 years with incident kidney failure in 2009 in the United States Renal Data System database. Exposure: Race/ethnicity (non-Hispanic Asian American [Asian-NH], non-Hispanic African American or Black [Black-NH], Hispanic, and non-Hispanic White [White-NH]) and age group (18-44 years and 45-64 years). Outcome: Ten-year KRT modality sequences (in-center dialysis, home dialysis, deceased donor kidney transplant [DDKT], living donor kidney transplant, stopped dialysis, and mortality). Analytical Approach: Using sequence analysis, longitudinal KRT modalities were characterized using descriptive statistics and visualized with state distribution plots, stratified by race/ethnicity and age. Results: The study included 50,776 adults with kidney failure (24% 18-44 years old and 76% 45-64 years old; 3.6% Asian-NH, 35.8% Black-NH, 17.7% Hispanic, and 42.9% White-NH). Among those aged 18-44, Hispanic and Asian-NH patients more frequently survived 10 years compared with Black-NH and White-NH patients. Among non-White patients, receipt of DDKT increased in years 4-6. Asian-NH patients had the highest DDKT receipt frequency. Asian-NH and White-NH patients more frequently experienced treatment sequences with 3 or more KRT modalities, and these sequences more commonly included transplant. Among patients initially receiving home dialysis, Asian-NH and White-NH patients more commonly transitioned to transplant compared with Black-NH and Hispanic patients. Compared with patients aged 18-44 years, racial/ethnic differences in KRT treatment sequences were attenuated among those aged 45-64 years. Limitations: Descriptive analyses cannot identify causal mechanisms. Excluding patients missing KRT modality may limit generalizability. Conclusions: Patterns in the KRT modality sequences offer a more nuanced view of racial/ethnic disparities in access to treatments for incident kidney failure.

Indexed as

ageKidney replacement therapylongitudinal analysispatient historyrace/ethnicitysequence analysis

Identifiers

PMID41510562
PMCPMC12775809

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