Evidence map›Paper›PMID 41510487›Full record

ArticleRespirology case reports2026

Three-Year Diagnostic Delay in Shrinking Lung Syndrome: Rituximab-Theophylline Combination as Rescue Therapy.

Somayeh Motamed, Alireza Mirzamohamadi, Shokufe Sadeghi, Vahid Ardestani Rostami, Mehrdad Mahalleh, Majid Alikhani

Abstract read
In one paragraph

Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Somayeh MotamedRheumatology Research Center Tehran University of Medical Sciences Tehran Iran.
Alireza MirzamohamadiRheumatology Research Center Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-6355-9851
Shokufe SadeghiRheumatology Research Center Tehran University of Medical Sciences Tehran Iran.
Vahid Ardestani RostamiRheumatology Research Center Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0009-0006-9852-2158
Mehrdad MahallehRheumatology Research Center Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-6210-2112
Majid AlikhaniRheumatology Research Center Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0009-0009-3954-9926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shrinking lung syndrome (SLS) is an infrequent complication of systemic lupus erythematosus (SLE). A 41-year-old woman with a 10-year history of SLE presented with dyspnea, chest pain, and dry cough. She had poor medication compliance and multiple hospitalizations over 3 years for similar symptoms, without a definitive diagnosis. Imaging revealed bilateral basal atelectasis and an elevated right hemidiaphragm, while pulmonary function tests (PFTs) showed a restrictive pattern. Other lung and cardiac conditions were excluded, leading to a diagnosis of SLS. Treatment with rituximab, prednisolone, and theophylline improved PFTs, chest pain, cough, and dyspnea at follow-up. Clinicians should consider SLS in SLE patients with dyspnea and characteristic imaging, as delayed diagnosis may increase morbidity.

Indexed as

case reportrituximabshrinking lung syndromesystemic lupus erythematosustheophylline

Identifiers

PMID41510487
PMCPMC12778291

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.