ReviewCureus2025
Impact of Laser Surface Modification on Zirconia Implants: A Systematic Review of In Vitro Evidence.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zirconia implants have emerged as a viable alternative to titanium due to their superior aesthetics, chemical stability, and biocompatibility. However, their inherently low surface bioactivity has resulted in the development of advanced surface modification techniques to improve osseointegration and biological performance. This systematic review evaluated in vitro studies investigating the effects of laser surface treatment on zirconia implants. A comprehensive electronic and manual search was conducted in PubMed, Cochrane Library, Google Scholar, Scopus, ScienceDirect, and EBSCOhost, including studies published after 2005. Nine in vitro studies met the inclusion criteria. The results demonstrated that laser irradiation significantly enhanced surface roughness, wettability, and protein adsorption while promoting osteoblastic adhesion, proliferation, and differentiation. Femtosecond and Nd:YAG lasers produced well-defined micro- and nano-topographies without inducing deleterious phase transformation or compromising mechanical integrity. Additionally, laser-treated zirconia exhibited reduced bacterial adhesion, suggesting improved antimicrobial potential. Despite methodological variations, all studies indicated positive biological and structural outcomes associated with laser modification. Laser surface modification thus represents a precise, reproducible, and contamination-free approach for enhancing zirconia implant performance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.