Evidence map›Paper›PMID 41510476›Full record

ArticleCureus2025

Idiopathic Hyperprolactinemia: Clinical Presentation, Diagnosis, Management, and Clinical Outcome.

Olabosipo Sholuade, Goodness Njoku, Suma Kaza, Reshma A Fatteh, Manoj Kollukkad, Charles Edwards

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olabosipo SholuadeMedical School, Avalon University School of Medicine, Willemstad, CUW.
Goodness NjokuMedical School, Avalon University School of Medicine, Willemstad, CUW.
Suma KazaPathology, Avalon University School of Medicine, Willemstad, CUW.
Reshma A FattehBehavioral Health and Psychiatry, Avalon University School of Medicine, Willemstad, CUW.
Manoj KollukkadHuman Structure and Function, Avalon University School of Medicine, Willemstad, CUW.
Charles EdwardsObstetrics and Gynecology, Avalon University School of Medicine, Willemstad, CUW.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is a multifactorial endocrine disorder often presenting with menstrual irregularities, hyperandrogenism, and metabolic dysfunction. Hyperprolactinemia, characterized by elevated prolactin levels, may share overlapping features with PCOS and complicate diagnosis. When these two conditions coexist, they present unique clinical and management challenges. A 25-year-old woman with a history of PCOS presented with amenorrhea, progressive weight gain, and irregular menstrual cycles. Laboratory investigations revealed persistently elevated prolactin levels, while pituitary imaging ruled out structural abnormalities. The patient received lifestyle modification advice and dopamine agonist therapy, with continuous monitoring of hormonal, metabolic, and psychological parameters. This case highlights the diagnostic complexity of idiopathic hyperprolactinemia occurring in the context of PCOS, and emphasizes the importance of a multidisciplinary approach to management. Further clinical observations are needed to understand the neuropsychiatric effects of prolactin dysregulation.

Indexed as

bromocriptine therapydopamine agonistshyperprolactinemia and mood disordershyperprolactinemia diagnosisidiopathic hyperprolactinemiapcos and hyperprolactinemiapituitary imagingprolactin dysregulation

Identifiers

PMID41510476
PMCPMC12777437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.